Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.36 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.34 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.34 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MITF | O75030 | 1/20 | 0.33 |
| ▸ | NSD2 | O96028 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.33 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.33 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | PTPRC | P08575 | 1/20 | 0.33 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.32 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | CDC25B | P30305 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45454 | 0.88 | CYP2C19 (0.33) | CASP3ALDH1A1LMNACYP2C19 | |
| SCHEMBL1039516 | 0.88 | ADRB2 (0.37) | CASP3ADRA1DADRA1AADRA1BALDH1A1 | |
| SCHEMBL7555105 | 0.78 | TSHR (0.36) | ALDH1A1KMT2ALMNAHTTL3MBTL1 | |
| SCHEMBL3258401 | 0.78 | CYP2A6 (0.34) | ALDH1A1KMT2AHTT | |
| SCHEMBL23390709 | 0.72 | — | — | |
| SCHEMBL624569 | 0.71 | CYP3A4 (0.39) | CASP3ALDH1A1KMT2ALMNAHTT | |
| Bromide SCHEMBL7610464 | 0.70 | CYP3A4 (0.38) | CASP3ALDH1A1KMT2ALMNAMEN1 | |
| SCHEMBL11896620 | 0.69 | ACHE (0.41) | ALDH1A1KMT2AHTTL3MBTL1CA12 | |
| SCHEMBL4449690 | 0.69 | TP53 (0.32) | ALDH1A1LMNAL3MBTL1CYP2C19 | |
| SCHEMBL14809988 | 0.68 | CYBB (0.33) | ALDH1A1KMT2AMEN1CDC25BCYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8198471-B2 | 2, 2′-bis (dialkylphosphino) biphenyl compound, production method thereof, and metal complex comprising the compound as ligand | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2012-06-12 | — | — | US | claimed |
| US-20100234626-A1 | 2, 2'-BIS (DIALKYLPHOSPHINO) BIPHENYL COMPOUND, PRODUCTION METHOD THEREOF, AND METAL COMPLEX COMPRISING THE COMPOUND AS LIGAND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2010-09-16 | — | — | US | claimed |
| US-8198471-B2 | 2, 2′-bis (dialkylphosphino) biphenyl compound, production method thereof, and metal complex comprising the compound as ligand | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2012-06-12 | — | — | US | disclosed |
| JP-2010208993-A | 2,2'-BIS(DIALKYLPHOSPHINO)BIPHENYL COMPOUND, METHOD FOR PRODUCING THE SAME, AND METAL COMPLEX USING THE COMPOUND AS LIGAND | NIPPON CHEM IND CO LTD | 2010-09-24 | — | — | JP | disclosed |
| US-20100234626-A1 | 2, 2'-BIS (DIALKYLPHOSPHINO) BIPHENYL COMPOUND, PRODUCTION METHOD THEREOF, AND METAL COMPLEX COMPRISING THE COMPOUND AS LIGAND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| US-20100234626-A1 | 2, 2'-BIS (DIALKYLPHOSPHINO) BIPHENYL COMPOUND, PRODUCTION METHOD THEREOF, AND METAL COMPLEX COMPRISING THE COMPOUND AS LIGAND | NIPPON CHEMICAL INDUSTRIAL CO., LTD. (JP) | 2010-09-16 | — | — | US | disclosed |
| WO-2010004139-A1 | NEW CYCLOALKYLATED BENZOTHIADIAZINE DERIVATIVES, METHOD FOR PREPARING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | LES LABORATOIRES SERVIER (FR) | 2010-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100234626-A1 | 2, 2'-BIS (DIALKYLPHOSPHINO) BIPHENYL COMPOUND, PRODUCTION METHOD THEREOF, AND METAL COMPLEX COMPRISING THE COMPOUND AS LIGAND | BMPR1A, ADORA1, BMPR1B | CASP3 3611/4885ADRA1D 1546/4885ADRA1A 1069/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.