SCHEMBL3262903

SCHEMBL3262903

Cc1cc2ccccc2c(-c2c(O)c(C)cc3ccccc23)c1O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.52
HTT P42858 1/20 0.52
PKM P14618 1/20 0.48
CYP2A6 P11509 3/20 0.48
CYP1A2 P05177 3/20 0.48
PTGS1 P23219 2/20 0.46
PTGS2 P35354 2/20 0.46
ALOX5 P09917 2/20 0.46
TRPM4 Q8TD43 1/20 0.45
MEN1 O00255 1/20 0.44
MAPT P10636 1/20 0.44
KMT2A Q03164 1/20 0.44
NQO2 P16083 1/20 0.43
ALDH1A1 P00352 3/20 0.43
HSD17B10 Q99714 2/20 0.42
HPGD P15428 1/20 0.42
NQO1 P15559 1/20 0.42
PTPN22 Q9Y2R2 1/20 0.40
ACHE P22303 1/20 0.40
TSHR P16473 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31277250 1.00 LMNA (0.52) LMNAHTTPKMCYP2A6CYP1A2
SCHEMBL14413583 0.92 LMNA (0.50) LMNAHTTPKMCYP2A6CYP1A2
SCHEMBL10586476 0.89 MEN1 (0.58) LMNAHTTCYP1A2PTGS1PTGS2
SCHEMBL10105268 0.89 LMNA (0.43) LMNAHTTPKMCYP2A6CYP1A2
SCHEMBL28339966 0.89 PKM (0.49) LMNAHTTPKMCYP2A6CYP1A2
SCHEMBL30535784 0.85 PTGS1 (0.46) LMNAHTTPKMCYP2A6CYP1A2
SCHEMBL8463472 0.85 POLB (0.56) HTTPKMCYP1A2MEN1MAPT
SCHEMBL4172887 0.84 LMNA (0.54) LMNAHTTPKMCYP2A6CYP1A2
SCHEMBL9618848 0.84 LMNA (0.50) LMNAHTTPKMCYP2A6CYP1A2
Methane SCHEMBL10776483 0.84 CYP1A2 (0.47) LMNAHTTPKMCYP2A6CYP1A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 53 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0471498-B1 Optical resolution method KANKYO KAGAKU CENTER (JP) 1997-12-17 EP claimed
WO-2023210363-A1 FLUORESCENT COMPOUND, METHOD FOR PRODUCING FLUORESCENT COMPOUND, AND WATER TREATMENT AGENT COMPOSITION オルガノ株式会社 2023-11-02 WO disclosed
US-9475989-B2 Binaphthyl compound, liquid crystal composition, liquid crystal element, and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2016-10-25 US disclosed
US-9061959-B2 Method for manufacturing optically active menthol TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-06-23 US disclosed
US-9061959-B2 Method for manufacturing optically active menthol TAKASAGO INTERNATIONAL CORPORATION (JP) 2015-06-23 US disclosed
US-8975447-B2 Process for asymetric methylallylation in the presence of a 2,2′-substituted 1,1′-BI-2-naphthol catalyst BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) 2015-03-10 US disclosed
US-8968841-B2 Binaphthyl compound, liquid crystal composition, liquid crystal element, and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-03-03 US disclosed
US-20150034869-A1 BINAPHTHYL COMPOUND, LIQUID CRYSTAL COMPOSITION, LIQUID CRYSTAL ELEMENT, AND LIQUID CRYSTAL DISPLAY DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2015-02-05 US disclosed
EP-2376411-B1 ALUMINIUM COMPLEXES AND USE THEREOF AS A CATALYST IN INTRAMOLECULAR RING CLOSURE REACTIONS TAKASAGO PERFUMERY CO LTD (JP) 2014-11-12 EP disclosed
US-8877302-B2 Liquid crystal composition, liquid crystal element, and liquid crystal display device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2014-11-04 US disclosed
US-6127567-A HYDROCYANATION OF AN ALIPHATIC MONOETHYLENICALLY UNSATURATED COMPOUND, USING A CATALYST PRECURSOR COMPOSITION OF ZERO-VALENT NICKEL, A LEWIS ACID, AND A MULTIDENTATE PHOSPHITE LIGAND OF GIVEN FORMULA; CATALYST SELECTIVITY E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-10-03 US disclosed
EP-1000019-A1 HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR E.I. du Pont de Nemours and Company (US) 2000-05-17 EP disclosed
US-5959135-A Hydrocyanation processes and multidentate phosphite ligand and nickel catalyst compositions thereof E. I. DU PONT DE NEMOURS AND COMPANY (US) 1999-09-28 US disclosed
WO-1999006356-A1 HYDROCYANATION PROCESSES AND MULTIDENTATE PHOSPHITE LIGAND AND NICKEL CATALYST COMPOSITIONS THEREFOR E.I. DU PONT DE NEMOURS AND COMPANY (US) 1999-02-11 WO disclosed
EP-0471498-B1 Optical resolution method KANKYO KAGAKU CENTER (JP) 1997-12-17 EP disclosed
US-5510520-A Optical resolution method KANKYO KAGAKU CENTER CO., LTD. (JP) 1996-04-23 US disclosed
US-5395962-A Optical resolution method KANKYO KAGAKU CENTER CO., LTD. (JP) 1995-03-07 US disclosed
EP-0471498-A2 Optical resolution method KANKYO KAGAKU CENTER CO., LTD (JP) 1992-02-19 EP disclosed
US-4284581-A LITHIUM 1,1'-BINAPHTHYL-2,2'-DIOXYALUMINUM HYDRIDE, REDUCING AGENTS ONO PHARMACEUTICAL CO., LTD. (JP) 1981-08-18 US disclosed
US-4043979-A Polymer-multiheteromacrocycles THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) 1977-08-23 US disclosed