Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 4/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 1/20 | 0.37 |
| ▸ | CA1 | P00915 | 1/20 | 0.37 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | CA7 | P43166 | 1/20 | 0.37 |
| ▸ | CA9 | Q16790 | 1/20 | 0.37 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | GLA | P06280 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263164 | 0.78 | PDE4D (0.39) | LMNAALDH1A1NPSR1HTTPKM | |
| SCHEMBL3263025 | 0.73 | PDE4D (0.60) | LMNAALDH1A1PDE4DSMN1; SMN2HSD17B10 | |
| SCHEMBL26926704 | 0.68 | KMT2A (0.47) | LMNAALDH1A1PDE4DCA12CA1 | |
| SCHEMBL24133585 | 0.66 | ALDH1A1 (0.46) | LMNAALDH1A1HTTPKMMAPK1 | |
| SCHEMBL3263297 | 0.66 | KDM4E (0.32) | NPSR1PKMKMT2AHPGD | |
| SCHEMBL31325016 | 0.65 | PDE4D (0.39) | LMNAALDH1A1NPSR1MAPK1PDE4D | |
| SCHEMBL3264755 | 0.64 | CA12 (0.33) | LMNAALDH1A1NPSR1HTTPKM | |
| SCHEMBL16708862 | 0.64 | KMT2A (0.46) | ALDH1A1NPSR1MAPK1PDE4DCA12 | |
| SCHEMBL26926815 | 0.63 | PDE4D (0.71) | ALDH1A1NPSR1HTTMAPK1PDE4D | |
| SCHEMBL24553751 | 0.63 | ELANE (0.39) | LMNAALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |