Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.37 |
| ▸ | LMNA | P02545 | 3/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.35 |
| ▸ | HTT | P42858 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | CA12 | O43570 | 1/20 | 0.34 |
| ▸ | CA1 | P00915 | 1/20 | 0.34 |
| ▸ | CA2 | P00918 | 1/20 | 0.34 |
| ▸ | CA7 | P43166 | 1/20 | 0.34 |
| ▸ | CA9 | Q16790 | 1/20 | 0.34 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262908 | 0.78 | LMNA (0.40) | PDE4DSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL3264753 | 0.72 | LMNA (0.61) | PDE4DSMN1; SMN2LMNAALDH1A1HPGD | |
| SCHEMBL3265324 | 0.67 | PDE4D (0.53) | PDE4DSMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL3263157 | 0.66 | CA12 (0.30) | CA12CA1CA2CA9 | |
| SCHEMBL18113731 | 0.65 | CA12 (0.48) | PDE4DSMN1; SMN2LMNAALDH1A1HTT | |
| SCHEMBL3260996 | 0.65 | PDE4D (0.69) | PDE4DSMN1; SMN2ALDH1A1MAPK1HTT | |
| SCHEMBL8813971 | 0.63 | LMNA (0.39) | PDE4DSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL1613436 | 0.63 | ALDH1A1 (0.43) | PDE4DSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL20709969 | 0.63 | ALDH1A1 (0.46) | PDE4DSMN1; SMN2LMNAALDH1A1MAPK1 | |
| SCHEMBL11008658 | 0.62 | ALDH1A1 (0.62) | PDE4DSMN1; SMN2LMNAALDH1A1MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015656-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151434-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |