Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.40 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.40 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 1/20 | 0.35 |
| ▸ | ACHE | P22303 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.34 |
| ▸ | MAOA | P21397 | 1/20 | 0.34 |
| ▸ | MAOB | P27338 | 1/20 | 0.34 |
| ▸ | SETD7 | Q8WTS6 | 1/20 | 0.34 |
| ▸ | MITF | O75030 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7055100 | 0.86 | CES1 (0.60) | CES1L3MBTL1TDP1AKR1B1RAB9A | |
| SCHEMBL29453593 | 0.82 | PNMT (0.46) | CES1SRD5A2RAB9ANPC1BCHE | |
| SCHEMBL784717 | 0.82 | PNMT (0.46) | CES1SRD5A2RAB9ANPC1BCHE | |
| SCHEMBL27537662 | 0.80 | PARP10 (0.46) | CES1L3MBTL1TDP1SRD5A1SRD5A2 | |
| SCHEMBL28109051 | 0.79 | SRD5A1 (0.49) | L3MBTL1TDP1SRD5A1SRD5A2PNMT | |
| Dihydrophenanthrene SCHEMBL155991 | 0.73 | CES1 (0.68) | CES1L3MBTL1TDP1SRD5A1SRD5A2 | |
| Dihydrophenanthrene SCHEMBL30297028 | 0.73 | CES1 (0.68) | CES1L3MBTL1TDP1SRD5A1SRD5A2 | |
| Dihydrophenanthrene SCHEMBL29404495 | 0.73 | CES1 (0.68) | CES1L3MBTL1TDP1SRD5A1SRD5A2 | |
| SCHEMBL8941775 | 0.73 | CYP2A6 (0.47) | CES1L3MBTL1SRD5A1SRD5A2DYRK1A | |
| SCHEMBL27346636 | 0.73 | CES1 (0.47) | CES1L3MBTL1SRD5A1SRD5A2DYRK1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7651746-B2 | Halogenated bisdiarylaminopolycyclic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2010-01-26 | — | — | US | disclosed |
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2007-06-07 | — | — | US | disclosed |
| WO-2005049546-A1 | HALOGENATED BISDIARYLAMINOPOLYCYLIC AROMATIC COMPOUNDS AND POLYMERS THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 2005-06-02 | — | — | WO | disclosed |
| EP-0397418-A1 | 9,10-dihydrophenanthrene-2,7-dicarboxylic acid diesters, 7-Bromo-9,10-dihydrophenanthrene-2-carboxylic acid esters and a process for producing the same | Director General, Agency of Industrial Science and Technology (JP) | 1990-11-14 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070126345-A1 | Halogenated bisdiarylaminopolycylic aromatic compounds and polymers thereof | AHR, AADAC, ARNT | CES1 3416/4885L3MBTL1 1104/4885TDP1 3715/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.