Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 2/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.54 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.52 |
| ▸ | MAOA | P21397 | 2/20 | 0.46 |
| ▸ | MAPK14 | Q16539 | 4/20 | 0.42 |
| ▸ | MAOB | P27338 | 3/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.40 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.40 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.39 |
| ▸ | MIF | P14174 | 4/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263050 | 0.86 | CES1 (0.47) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL8076308 | 0.83 | CES1 (0.59) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL13712393 | 0.78 | CES1 (1.00) | CES1TDP1L3MBTL1MAOAMAOB | |
| SCHEMBL29408351 | 0.78 | CES1 (0.90) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL44496 | 0.78 | CES1 (0.90) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL29437756 | 0.78 | CES1 (0.90) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL7525372 | 0.76 | AKR1B1 (0.63) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL16163913 | 0.75 | TDP1 (0.66) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL1306661 | 0.74 | TDP1 (0.80) | CES1TDP1L3MBTL1AKR1B1MAOA | |
| SCHEMBL4175611 | 0.72 | CES1 (0.59) | CES1TDP1L3MBTL1AKR1B1MAOA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042268-B1 | 1,7-DIBROMODIBENZOSUBERONE AND PROCEDURES FOR ITS PREPARATION | BELUPO LIJEKOVI I KOZMETIKA D (HR) | 2003-05-07 | — | — | EP | disclosed |