Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 6/20 | 0.53 |
| ▸ | MAPT | P10636 | 5/20 | 0.53 |
| ▸ | TP53 | P04637 | 2/20 | 0.53 |
| ▸ | NPC1 | O15118 | 2/20 | 0.53 |
| ▸ | RAB9A | P51151 | 2/20 | 0.53 |
| ▸ | ALOX5 | P09917 | 4/20 | 0.52 |
| ▸ | PTGES | O14684 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | ALPL | P05186 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TNF | P01375 | 1/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
| ▸ | CCR6 | P51684 | 1/20 | 0.44 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262663 | 0.88 | SMN1; SMN2 (0.51) | LMNAMAPTNPC1RAB9AALOX5 | |
| SCHEMBL3261384 | 0.74 | LMNA (0.57) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL3260996 | 0.72 | PDE4D (0.69) | MAPTNPSR1MAPK1HTTALDH1A1 | |
| SCHEMBL13495321 | 0.72 | SMN1; SMN2 (0.53) | LMNAMAPTNPC1RAB9AALOX5 | |
| SCHEMBL6228465 | 0.72 | KMT2A (0.51) | LMNAMAPTNPC1RAB9AALOX5 | |
| SCHEMBL3265324 | 0.71 | PDE4D (0.53) | MAPTNPSR1MAPK1HTTALDH1A1 | |
| SCHEMBL25382643 | 0.71 | SMN1; SMN2 (0.52) | LMNAMAPTNPC1RAB9AALOX5 | |
| SCHEMBL20897262 | 0.71 | ALPL (0.64) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL7828097 | 0.71 | LMNA (0.50) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL7675758 | 0.71 | ALOX5 (0.55) | LMNAMAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |