Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | TP53 | P04637 | 2/20 | 0.57 |
| ▸ | NPC1 | O15118 | 1/20 | 0.57 |
| ▸ | RAB9A | P51151 | 1/20 | 0.57 |
| ▸ | ALOX5 | P09917 | 7/20 | 0.56 |
| ▸ | PTGES | O14684 | 1/20 | 0.53 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | TNF | P01375 | 1/20 | 0.50 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.50 |
| ▸ | CCR6 | P51684 | 1/20 | 0.50 |
| ▸ | RUNX1 | Q01196 | 1/20 | 0.50 |
| ▸ | CBFB | Q13951 | 1/20 | 0.50 |
| ▸ | HKDC1 | Q2TB90 | 1/20 | 0.50 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.50 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262242 | 0.86 | SMN1; SMN2 (0.56) | LMNAMAPTNPC1RAB9AALOX5 | |
| SCHEMBL1659952 | 0.76 | CYP1A2 (0.49) | LMNAMAPTNPSR1KDM4EALDH1A1 | |
| SCHEMBL11811537 | 0.75 | LMNA (0.55) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL3263160 | 0.74 | LMNA (0.53) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL7675758 | 0.74 | ALOX5 (0.55) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL7675763 | 0.71 | ALOX5 (0.51) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL22272868 | 0.70 | LMNA (0.54) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL27294436 | 0.70 | PRKCZ (0.54) | LMNAMAPTTP53NPC1RAB9A | |
| SCHEMBL4558554 | 0.69 | ALOX5 (1.00) | ALOX5PTGES | |
| SCHEMBL11273877 | 0.69 | CSF1R (0.49) | LMNAMAPTTP53NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |