SCHEMBL3263157

SCHEMBL3263157

CCOc1nn(S(C)(=O)=O)c(C(F)(F)F)c1I

nearest known ligand 0.30

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.30
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30
CA9 Q16790 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3263297 0.73 KDM4E (0.32)
SCHEMBL3263504 0.64 CA12 (0.34) CA12CA1CA2CA9
SCHEMBL3264755 0.59 CA12 (0.33) CA12CA1CA2CA9
SCHEMBL3263071 0.58 LRRK2 (0.32)
SCHEMBL26924196 0.56 MAPT (0.36)
SCHEMBL24677206 0.55 L3MBTL1 (0.38)
SCHEMBL31206681 0.55 MEN1 (0.34)
SCHEMBL26954258 0.55 MEN1 (0.31)
SCHEMBL19105613 0.53 PTGS2 (0.39)
SCHEMBL26337591 0.53 PTGS2 (0.40) CA12CA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010015657-A2 NEW ALKOXYPYRAZOLES INSTITUT PASTEUR (FR) 2010-02-11 WO disclosed
WO-2010015657-A2 NEW ALKOXYPYRAZOLES INSTITUT PASTEUR (FR) 2010-02-11 WO disclosed
EP-2151433-A1 Alkoxypyrazoles and the process for their preparation Institut Pasteur (FR) 2010-02-10 EP disclosed
EP-2151433-A1 Alkoxypyrazoles and the process for their preparation Institut Pasteur (FR) 2010-02-10 EP disclosed