Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAP3K14 | Q99558 | 1/20 | 0.43 |
| ▸ | CRBN | Q96SW2 | 4/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | APEX1 | P27695 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | DDB1 | Q16531 | 3/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28384946 | 0.79 | MAP3K14 (0.35) | MAP3K14CRBNALDH1A1TDP1MEN1 | |
| SCHEMBL6511682 | 0.77 | MAP3K14 (0.43) | MAP3K14CRBNALDH1A1TDP1MEN1 | |
| SCHEMBL21658858 | 0.76 | MAP3K14 (0.46) | MAP3K14CRBNALDH1A1TDP1MEN1 | |
| SCHEMBL11130524 | 0.74 | MAP3K14 (0.34) | MAP3K14ALDH1A1TDP1MEN1APEX1 | |
| SCHEMBL11130527 | 0.74 | MAP3K14 (0.34) | MAP3K14ALDH1A1TDP1MEN1APEX1 | |
| SCHEMBL2711511 | 0.74 | MAP3K14 (0.44) | MAP3K14CRBNALDH1A1TDP1MEN1 | |
| SCHEMBL514603 | 0.74 | ALDH1A1 (0.52) | MAP3K14CRBNALDH1A1TDP1MEN1 | |
| SCHEMBL28499087 | 0.73 | EPHX2 (0.39) | KMT2AGLA | |
| SCHEMBL2896147 | 0.72 | MEN1 (0.47) | MAP3K14CRBNALDH1A1TDP1MEN1 | |
| SCHEMBL1530916 | 0.72 | CRBN (0.41) | MAP3K14CRBNALDH1A1TDP1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1712601-B1 | Phase change inks | XEROX CORP (US) | 2010-07-28 | — | — | EP | disclosed |