Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.48 |
| ▸ | DRD4 | P21917 | 1/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 2/20 | 0.45 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | KDM1A | O60341 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263279 | 0.87 | DRD4 (0.50) | POLBDRD4TRPV1KMT2ATP53 | |
| SCHEMBL3226550 | 0.81 | KDM1A (0.61) | ALDH1A1KDM1AHDAC1 | |
| SCHEMBL3263684 | 0.77 | KDM1A (0.50) | POLBKMT2AMEN1TP53KDM1A | |
| SCHEMBL1966404 | 0.77 | DRD4 (0.51) | POLBDRD4TRPV1KMT2AMEN1 | |
| SCHEMBL3262609 | 0.75 | KDM1A (0.49) | POLBRXFP1KDM1AHDAC1 | |
| SCHEMBL14073127 | 0.72 | TSHR (0.58) | TSHRPOLBKMT2AMEN1MAPT | |
| SCHEMBL3278485 | 0.72 | MAPK1 (0.65) | ALDH1A1KDM1AHDAC1 | |
| SCHEMBL14072363 | 0.72 | MMP8 (0.48) | TSHRDRD4TRPV1KMT2AKDM1A | |
| SCHEMBL531798 | 0.70 | TSHR (0.74) | TSHRTP53MAPTALDH1A1 | |
| SCHEMBL17092920 | 0.70 | MAOA (0.84) | TSHRDRD4KDM1AHDAC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023446-A1 | NOVEL POTASSIUM CHANNEL BLOCKERS | XENTION LIMITED (GB) | 2010-03-04 | — | — | WO | claimed |