Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3263298 | 0.70 | KMT2A (0.32) | — | |
| SCHEMBL187172 | 0.64 | — | — | |
| SCHEMBL11399968 | 0.60 | MTNR1A (0.62) | — | |
| SCHEMBL217915 | 0.55 | — | — | |
| SCHEMBL10938959 | 0.54 | MAPT (0.60) | — | |
| SCHEMBL12245992 | 0.54 | CHRNB2 (0.53) | KDM4E | |
| SCHEMBL5986952 | 0.54 | CHRNB2 (0.53) | KDM4E | |
| SCHEMBL2301974 | 0.53 | — | — | |
| SCHEMBL24925818 | 0.52 | OPRM1 (0.49) | KDM4E | |
| SCHEMBL24925839 | 0.52 | OPRM1 (0.49) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7799932-B2 | N-substituted 3,4-alkylenedioxypyrroles, ester substituted dihydroxypyrroles and methods for synthesis of these pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| EP-1931630-B1 | N-SUBSTITUTED 3,4-ALKYLENEDIOXYPYRROLES, ESTER SUBSTITUTED DIHYDROXYPYRROLES AND METHODS FOR SYNTHESIS OF THESE PYRROLES | UNIV FLORIDA (US) | 2010-05-12 | — | — | EP | disclosed |
| US-20090149661-A1 | N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2009-06-11 | — | — | US | disclosed |
| EP-1931630-A1 | N-SUBSTITUTED 3,4-ALKYLENEDIOXYPYRROLES, ESTER SUBSTITUTED DIHYDROXYPYRROLES AND METHODS FOR SYNTHESIS OF THESE PYRROLES | University of Florida Research Foundation, Incorporated (US) | 2008-06-18 | — | — | EP | disclosed |
| WO-2007041724-A1 | N-SUBSTITUTED 3,4-ALKYLENEDIOXYPYRROLES, ESTER SUBSTITUTED DIHYDROXYPYRROLES AND METHODS FOR SYNTHESIS OF THESE PYRROLES | UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INC. (US) | 2007-04-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090149661-A1 | N-Substituted 3,4-Alkylenedioxypyrroles, Ester Substituted Dihydroxypyrroles and Methods for Synthesis of These Pyrroles | PAH, DDT, DHPS | KDM4E 678/4885GLA 4243/4885TDP1 1924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.