Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.67 |
| ▸ | RAB9A | P51151 | 6/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.65 |
| ▸ | LMNA | P02545 | 5/20 | 0.65 |
| ▸ | MITF | O75030 | 1/20 | 0.65 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.65 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | MAPT | P10636 | 9/20 | 0.62 |
| ▸ | NPC1 | O15118 | 5/20 | 0.62 |
| ▸ | MEN1 | O00255 | 2/20 | 0.62 |
| ▸ | HTT | P42858 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.62 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.62 |
| ▸ | GAA | P10253 | 3/20 | 0.60 |
| ▸ | PKM | P14618 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10513594 | 0.87 | RAB9A (0.65) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL11063138 | 0.87 | NR4A2 (0.56) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL27854856 | 0.86 | NR4A2 (0.69) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL1559343 | 0.85 | NR4A2 (0.63) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL2355240 | 0.85 | NR4A2 (0.63) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL5705595 | 0.85 | NR4A2 (0.67) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL25445916 | 0.83 | NR4A2 (0.65) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL3624515 | 0.83 | NR4A2 (0.65) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| SCHEMBL591759 | 0.83 | ALDH1A1 (0.68) | NR4A2RAB9AKMT2AALDH1A1LMNA | |
| Pyrazinoic Acid SCHEMBL6968007 | 0.82 | KDM4E (0.51) | NR4A2RAB9AKMT2AALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 132 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-106083691-B | A kind of preparation method of arbidol HCl monohydrate | 山东罗欣药业集团恒欣药业有限公司 | 2018-11-27 | — | — | CN | claimed |
| EP-2217597-B1 | QUINUCLIDIN-4-YLMETHYL 1H-INDOLE-3-CARBOXYLATE DERIVATIVES AS ALPHA 7 NICOTINIC ACETYLCHOLINE RECEPTOR LIGANDS FOR THE TREATMENT OF ALZHEIMER'S DISEASE | COMENTIS INC (US) | 2011-03-30 | — | — | EP | claimed |
| CN-117756785-A | Preparation and application of N- (pyridine-2-yl) benzo [ b ] five-membered heterocycle-3-carboxamide structure compound | 江西中医药大学 | 2024-03-26 | — | — | CN | disclosed |
| CN-117603123-A | Novel indole HDAC6 small molecule inhibitor, preparation method and application | 郑州大学 | 2024-02-27 | — | — | CN | disclosed |
| US-11891386-B2 | Indole compounds and their use | ARIAGEN, INC. (CA) | 2024-02-06 | — | — | US | disclosed |
| CN-116964050-A | Compounds useful as T cell activators | 戈萨默生物服务公司 | 2023-10-27 | — | — | CN | disclosed |
| EP-4262986-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | Gossamer Bio Services, Inc. (US) | 2023-10-25 | — | — | EP | disclosed |
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | GOSSAMER BIO SERVICES INC (US) | 2023-08-31 | — | — | US | disclosed |
| EP-4215526-A1 | CARBONYL HETEROCYCLIC COMPOUND AND APPLICATION THEREOF | Shanghai Pharmaceuticals Holding Co., Ltd. (CN) | 2023-07-26 | — | — | EP | disclosed |
| US-20230145074-A1 | Indole Compounds and Their Use | ARIAGEN, INC. (US) | 2023-05-11 | — | — | US | disclosed |
| US-20230054194-A1 | Methods of Treating Cancer | ARIAGEN, INC. (US) | 2023-02-23 | — | — | US | disclosed |
| EP-0600955-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1994-06-15 | — | — | EP | disclosed |
| EP-0590152-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1994-04-06 | — | — | EP | disclosed |
| WO-1993003725-A1 | 5-HT4 RECEPTOR ANTAGONISTS | SMITHKLINE BEECHAM PLC (GB) | 1993-03-04 | — | — | WO | disclosed |
| WO-1992022569-A1 | PEPTIDES WITH TACHYKININ ANTAGONIST ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-12-23 | — | — | WO | disclosed |
| WO-1992014727-A1 | 3-PIPERIDINYLMETHYLCARBOXYLATE SUBSTITUTED INDOLES | GLAXO GROUP LIMITED (GB) | 1992-09-03 | — | — | WO | disclosed |
| EP-0144986-B1 | INDOLE-3-CARBOXAMIDE DERIVATIVES | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-03-04 | — | — | EP | disclosed |
| US-4616009-A | PSYCHOLOGICAL DISORDERS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1986-10-07 | — | — | US | disclosed |
| EP-0144986-A2 | Indole-3-carboxamide derivatives | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1985-06-19 | — | — | EP | disclosed |
| US-3980667-A | Anti-arrhythmic 5-endo-substituted oxy-N-(aminoloweralkyl)bicycle [2.2.2.]oc | BRISTOL-MYERS COMPANY (US) | 1976-09-14 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20230271954-A1 | COMPOUNDS USEFUL AS T CELL ACTIVATORS | DGKZ, DGKA, DGKG | NR4A2 2350/4885RAB9A 1071/4885KMT2A 2679/4885 |
| US-11891386-B2 | Indole compounds and their use | IDO1, IDO2, INMT | NR4A2 1539/4885RAB9A 3025/4885KMT2A 1124/4885 |
| US-20230054194-A1 | Methods of Treating Cancer | TP53, MSH2, PDCD1 | NR4A2 3628/4885RAB9A 4066/4885KMT2A 1118/4885 |
| US-20230145074-A1 | Indole Compounds and Their Use | IDO1, IDO2, INMT | NR4A2 1539/4885RAB9A 3025/4885KMT2A 1124/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.