Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.50 |
| ▸ | GAA | P10253 | 6/20 | 0.50 |
| ▸ | TP53 | P04637 | 4/20 | 0.50 |
| ▸ | NPC1 | O15118 | 6/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.47 |
| ▸ | RAB9A | P51151 | 5/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | VDR | P11473 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.42 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3387691 | 0.90 | SMN1; SMN2 (0.56) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL3393032 | 0.79 | ATM (0.46) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL31500065 | 0.76 | NPC1 (0.56) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL3264256 | 0.75 | GAA (0.41) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL3261589 | 0.75 | MAPT (0.43) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL3262218 | 0.75 | NPSR1 (0.49) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL3265133 | 0.75 | NPSR1 (0.45) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL27861242 | 0.74 | SMN1; SMN2 (0.65) | MAPTTP53NPC1SMN1; SMN2RAB9A | |
| SCHEMBL4191056 | 0.69 | GAA (0.55) | MAPTGAATP53NPC1SMN1; SMN2 | |
| SCHEMBL3385375 | 0.68 | RAB9A (0.45) | MAPTNPC1SMN1; SMN2RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |