Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 9/20 | 0.56 |
| ▸ | NPC1 | O15118 | 8/20 | 0.56 |
| ▸ | RAB9A | P51151 | 8/20 | 0.56 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | HPGD | P15428 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 7/20 | 0.47 |
| ▸ | TP53 | P04637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.45 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.45 |
| ▸ | RELA | Q04206 | 1/20 | 0.45 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3264193 | 0.90 | MAPT (0.50) | SMN1; SMN2NPC1RAB9AHIF1APOLB | |
| SCHEMBL3262218 | 0.80 | NPSR1 (0.49) | SMN1; SMN2NPC1RAB9AHIF1APOLB | |
| SCHEMBL3265133 | 0.80 | NPSR1 (0.45) | SMN1; SMN2NPC1RAB9AHIF1APOLB | |
| SCHEMBL3385375 | 0.76 | RAB9A (0.45) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| SCHEMBL27861242 | 0.76 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AHIF1APOLB | |
| SCHEMBL31500060 | 0.75 | SMN1; SMN2 (0.69) | SMN1; SMN2NPC1RAB9AHIF1APOLB | |
| SCHEMBL8765128 | 0.74 | SMN1; SMN2 (0.67) | SMN1; SMN2NPC1RAB9AHIF1APOLB | |
| SCHEMBL14132909 | 0.72 | SMN1; SMN2 (0.65) | SMN1; SMN2NPC1RAB9AHIF1APOLB | |
| SCHEMBL11577752 | 0.72 | SMN1; SMN2 (1.00) | SMN1; SMN2NPC1RAB9APOLBHPGD | |
| SCHEMBL9162850 | 0.71 | BCL2 (0.47) | SMN1; SMN2NPC1RAB9APOLBHPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |