Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GAA | P10253 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 4/20 | 0.40 |
| ▸ | TP53 | P04637 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.36 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.35 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.34 |
| ▸ | CACNA2D2 | Q9NY47 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3262218 | 0.85 | NPSR1 (0.49) | GAANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3261589 | 0.82 | MAPT (0.43) | GAANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3264376 | 0.77 | CYP1A2 (0.40) | GAANPC1RAB9ASMN1; SMN2POLB | |
| SCHEMBL3264571 | 0.76 | RAB9A (0.42) | NPC1RAB9ASMN1; SMN2MAPTTP53 | |
| SCHEMBL14151614 | 0.76 | SMN1; SMN2 (0.49) | GAANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3264193 | 0.75 | MAPT (0.50) | GAANPC1RAB9ASMN1; SMN2MAPT | |
| SCHEMBL3386827 | 0.71 | POLB (0.46) | MAPTPOLB | |
| SCHEMBL3387671 | 0.70 | POLB (0.69) | GAASMN1; SMN2MAPTTP53POLB | |
| SCHEMBL3262684 | 0.69 | PDE5A (0.30) | — | |
| SCHEMBL3264878 | 0.68 | CYP1A2 (0.40) | GAANPC1RAB9ASMN1; SMN2POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010015657-A2 | NEW ALKOXYPYRAZOLES | INSTITUT PASTEUR (FR) | 2010-02-11 | — | — | WO | disclosed |
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |