Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.42 |
| ▸ | MAPT | P10636 | 4/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.41 |
| ▸ | HPGD | P15428 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 6/20 | 0.41 |
| ▸ | RAB9A | P51151 | 6/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 3/20 | 0.40 |
| ▸ | BCL2 | P10415 | 1/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.39 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | CNR1 | P21554 | 1/20 | 0.38 |
| ▸ | CNR2 | P34972 | 1/20 | 0.38 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3385375 | 0.90 | RAB9A (0.45) | MAPTSMN1; SMN2HPGDNPC1RAB9A | |
| SCHEMBL3263308 | 0.85 | NPSR1 (0.40) | MAPTLMNASMN1; SMN2HPGDNPC1 | |
| SCHEMBL3261292 | 0.80 | ALDH1A1 (0.46) | GAAMAPTSMN1; SMN2NPC1RAB9A | |
| SCHEMBL3262693 | 0.79 | ATM (0.42) | ATMMAPTLMNAHPGDNPC1 | |
| SCHEMBL3264193 | 0.79 | MAPT (0.50) | ATMGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL3260654 | 0.78 | MAPT (0.50) | ATMMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL4191056 | 0.77 | GAA (0.55) | GAAMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL3264381 | 0.77 | TRPM8 (0.43) | ATMGAAMAPTLMNASMN1; SMN2 | |
| SCHEMBL3264346 | 0.75 | KDM4E (0.43) | ATMMAPTLMNASMN1; SMN2HPGD | |
| SCHEMBL3264376 | 0.75 | CYP1A2 (0.40) | ATMGAALMNASMN1; SMN2NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2151433-A1 | Alkoxypyrazoles and the process for their preparation | Institut Pasteur (FR) | 2010-02-10 | — | — | EP | disclosed |