SCHEMBL326451

SCHEMBL326451

CCCCCCC(CCCCCC)(CCCCCC)CCCCCC(CCCCCC)(C(=O)OCC)C(CCCCCC)(CCCCCC)C(CCCCCC)(CCCCCC)C(CCCCCC)(CCCCCC)C(CCCCCC)(CCCCCC)C(CCCCCC)(CCCCCC)C(CCCCCC)(CCCCCC)CCCCCC

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.46
KMT2A Q03164 2/20 0.46
MAPT P10636 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
CYP4F2 P78329 2/20 0.40
CYP4A11 Q02928 2/20 0.40
HTT P42858 1/20 0.39
THRB P10828 1/20 0.36
PKM P14618 1/20 0.36
CES2 O00748 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
FAAH O00519 2/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8673442 0.95 MEN1 (0.49) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL3838857 0.93 MEN1 (0.47) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL7691355 0.93 MEN1 (0.47) MEN1KMT2AMAPTATML3MBTL1
Acetic Acid SCHEMBL888002 0.91 MEN1 (0.49) MEN1KMT2AMAPTATML3MBTL1
Acetic Acid SCHEMBL215134 0.89 ATM (0.47) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL2731548 0.87 MAPT (0.43) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL973726 0.87 MAPT (0.43) MEN1KMT2AMAPTATML3MBTL1
Acetic Acid SCHEMBL5604746 0.85 MEN1 (0.46) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL371118 0.84 MEN1 (0.40) MEN1KMT2AMAPTATML3MBTL1
SCHEMBL10612416 0.83 NAAA (0.44) MEN1KMT2AMAPTATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 118 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11999818-B2 High molecular weight triarylamine compound comprising terphenyl structure in molecular main chain and organic electroluminescent element comprising said high molecular weight compound HODOGAYA CHEMICAL CO., LTD. (JP) 2024-06-04 US disclosed
US-11834421-B2 Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof JAPAN TOBACCO INC. (JP) 2023-12-05 US disclosed
CN-111741948-B Saturated ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof 日本烟草产业株式会社 2023-11-10 CN disclosed
EP-3760619-B1 SATURATED RING-CONDENSED DIHYDROPYRIMIDINONE OR DIHYDROTRIAZINONE COMPOUND, AND PHARMACEUTICAL USE THEREOF JAPAN TOBACCO INC (JP) 2023-10-25 EP disclosed
US-20220209129-A1 PYRIDINE-CARBONITRILE COMPOUND AND ELECTROLUMINESCENT DEVICE INCLUDING THE SAME NATIONAL TSING HUA UNIVERSITY (TW) 2022-06-30 US disclosed
CN-114644617-A Cyanopyridine compound and electroluminescent device comprising the same 郑建鸿 2022-06-21 CN disclosed
US-20220119355-A1 SATURATED-RING-FUSED DIHYDROPYRIMIDINONE OR DIHYDROTRIAZINONE COMPOUNDS AND PHARMACEUTICAL USE THEREOF SHIONOGI & CO., LTD. (JP) 2022-04-21 US disclosed
US-20210253785-A1 HIGH MOLECULAR WEIGHT TRIARYLAMINE COMPOUND COMPRISING TERPHENYL STRUCTURE IN MOLECULAR MAIN CHAIN AND ORGANIC ELECTROLUMINESCENT ELEMENT COMPRISING SAID HIGH MOLECULAR WEIGHT COMPOUND HODOGAYA CHEMICAL CO., LTD. (JP) 2021-08-19 US disclosed
EP-3760619-A1 SATURATED RING-CONDENSED DIHYDROPYRIMIDINONE OR DIHYDROTRIAZINONE COMPOUND, AND PHARMACEUTICAL USE THEREOF Japan Tobacco Inc. (JP) 2021-01-06 EP disclosed
EP-3184112-B1 SYNTHETIC INTERMEDIATE OF 1-(2-DEOXY-2-FLUORO-4-THIO-ß-D-ARABINOFURANOSYL)CYTOSINE FUJIFILM CORP (JP) 2020-12-23 EP disclosed
CN-1100417-A N-heteroaryl-n'-phenylurea derivatives, their production and use NIHON NOHYAKU CO LTD (JP) 1995-03-22 CN disclosed
US-5348933-A Triazine substituted compounds ISHIHARA SANGYO KAISHA, LTD. (JP) 1994-09-20 US disclosed
EP-0613894-A1 N-Heteroaryl-N'-phenylurea derivatives, their production and use NIHON NOHYAKU CO., LTD. (JP) 1994-09-07 EP disclosed
EP-0592306-A2 19F-MRI Contrast medium TERUMO KABUSHIKI KAISHA (JP) 1994-04-13 EP disclosed
US-5288727-A Hydrazone compounds, processes for their production, intermediates useful for their production and pesticidal compositions containing them ISHIHARA SANGYO KAISHA LTD. (JP) 1994-02-22 US disclosed
CN-1077453-A Substituted pyridinesulfonamide compound or its salt prepare its method and the weedicide that contains it ISHIHARA SANGYO KAISHA (JP) 1993-10-20 CN disclosed
EP-0562731-A1 Substituted pyridinesulfonamide compounds or their salts, process for preparing the same, and herbicides containing the same ISHIHARA SANGYO KAISHA, Ltd. (JP) 1993-09-29 EP disclosed
EP-0540697-A1 NOVEL SULFONYLUREAS Novartis AG (CH) 1993-05-12 EP disclosed
WO-1992016522-A1 NOVEL SULFONYLUREAS CIBA-GEIGY AG (CH) 1992-10-01 WO disclosed
EP-0500111-A2 Hydrazone compounds, processes for their production, intermediates useful for their production and pesticidal compositions containing them ISHIHARA SANGYO KAISHA, LTD. (JP) 1992-08-26 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20220209129-A1 PYRIDINE-CARBONITRILE COMPOUND AND ELECTROLUMINESCENT DEVICE INCLUDING THE SAME ARL1, RCN1, AR MEN1 582/4885KMT2A 1823/4885MAPT 2735/4885
US-11834421-B2 Saturated-ring-fused dihydropyrimidinone or dihydrotriazinone compounds and pharmaceutical use thereof RORC, RORB, RORA MEN1 3985/4885KMT2A 1904/4885MAPT 1809/4885
US-20220119355-A1 SATURATED-RING-FUSED DIHYDROPYRIMIDINONE OR DIHYDROTRIAZINONE COMPOUNDS AND PHARMACEUTICAL USE THEREOF RORC, RORB, RORA MEN1 3985/4885KMT2A 1904/4885MAPT 1809/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.