Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES2 | O00748 | 2/20 | 0.64 |
| ▸ | MEN1 | O00255 | 1/20 | 0.56 |
| ▸ | THRB | P10828 | 1/20 | 0.56 |
| ▸ | HTT | P42858 | 1/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 1/20 | 0.56 |
| ▸ | TSHR | P16473 | 4/20 | 0.50 |
| ▸ | NAAA | Q02083 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.47 |
| ▸ | HCAR2 | Q8TDS4 | 2/20 | 0.47 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.46 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.45 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.44 |
| ▸ | SLC22A8 | Q8TCC7 | 1/20 | 0.44 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARD | Q03181 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL353029 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL3139068 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL3426392 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL4930252 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL2400937 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL28328015 | 0.97 | CES2 (0.61) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL138223 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL2863329 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL537713 | 0.97 | CES2 (0.68) | CES2MEN1THRBHTTKMT2A | |
| Acetic Acid SCHEMBL9550103 | 0.95 | CES2 (0.65) | CES2MEN1THRBHTTKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107207902-B | Easily peelable protective resin film-forming composition | 日产化学工业株式会社 | 2020-11-06 | — | — | CN | disclosed |
| EP-1490501-B1 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | REDDY S LAB EU LTD DR (GB) | 2010-05-26 | — | — | EP | disclosed |
| US-7264960-B2 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | DOW GLOBAL TECHNOLOGIES INC. (US) | 2007-09-04 | — | — | US | disclosed |
| US-20050026260-A1 | Enzymatic resolution of propylene glycol alkyl (or aryl) ethers and ether acetates | RESNICK SOL M (US) | 2005-02-03 | — | — | US | disclosed |
| EP-1490501-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | Dow Global Technologies Inc. (US) | 2004-12-29 | — | — | EP | disclosed |
| WO-2003083126-A2 | ENZYMATIC RESOLUTION OF PROPYLENE GLYCOL ALKYL (OR ARYL) ETHERS AND ETHER ACETATES | DOW GLOBAL TECHNOLOGIES INC. (US) | 2003-10-09 | — | — | WO | disclosed |