Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 known ✓ | P03372 | 1/20 | 0.48 |
| ▸ | CES2 | O00748 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | HTT | P42858 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.60 |
| ▸ | NAAA | Q02083 | 1/20 | 0.52 |
| ▸ | TSHR | P16473 | 5/20 | 0.52 |
| ▸ | PLA2G2C | Q5R387 | 2/20 | 0.50 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.48 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 5/20 | 0.48 |
| ▸ | PPARD | Q03181 | 5/20 | 0.48 |
| ▸ | PPARA | Q07869 | 5/20 | 0.48 |
| ▸ | HDAC11 | Q96DB2 | 4/20 | 0.48 |
| ▸ | GPR84 | Q9NQS5 | 3/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | TLR2 | O60603 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acetic Acid SCHEMBL138223 | 1.00 | CES2 (0.68) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL4930252 | 1.00 | CES2 (0.68) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL353029 | 1.00 | CES2 (0.68) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL2400937 | 1.00 | CES2 (0.68) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL3426392 | 1.00 | CES2 (0.68) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL3139068 | 1.00 | CES2 (0.68) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL2863329 | 1.00 | CES2 (0.68) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL9550103 | 0.98 | CES2 (0.65) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL3264543 | 0.97 | CES2 (0.64) | CES2MEN1KMT2ATHRBHTT | |
| Acetic Acid SCHEMBL28328015 | 0.95 | CES2 (0.61) | CES2MEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11207263-B2 | Cosmetic compositions | DOW SILICONES CORPORATION (US) | 2021-12-28 | — | — | US | claimed |
| US-20200237639-A1 | COSMETIC COMPOSITIONS | DOW SILICONES CORP (US) | 2020-07-30 | — | — | US | claimed |
| US-20200222302-A1 | FILM FORMING COMPOSITIONS HAVING A TACK-FREE SURFACE | DOW SILICONES CORPORATION | 2020-07-16 | — | — | US | claimed |
| WO-2019045831-A1 | FILM FORMING COMPOSITIONS HAVING A TACK-FREE SURFACE | DOW SILICONES CORPORATION (US) | 2019-03-07 | — | — | WO | claimed |
| WO-2019045830-A1 | COSMETIC COMPOSITIONS | DOW SILICONES CORPORATION (US) | 2019-03-07 | — | — | WO | claimed |
| CN-101835457-B | Two-part hair dye | 花王株式会社 | 2016-10-12 | — | — | CN | claimed |
| CN-103079532-B | Two-part foam hair dye | KAO CORP | 2015-03-25 | — | — | CN | claimed |
| US-8636812-B2 | Two-part foam hair dye | KAO CORPORATION (JP) | 2014-01-28 | — | — | US | claimed |
| EP-2612651-A1 | TWO-LIQUID TYPE FOAM HAIR DYE | Kao Corporation (JP) | 2013-07-10 | — | — | EP | claimed |
| US-20130125918-A1 | TWO-PART FOAM HAIR DYE | KAO CORPORATION (JP) | 2013-05-23 | — | — | US | claimed |
| CN-103079532-A | Two-part foam hair dye | KAO CORP | 2013-05-01 | — | — | CN | claimed |
| US-5008100-A | Stable sunscreens | ELIZABETH ARDEN CO., DIVISION OF CONOPCO, INC. (US) | 1991-04-16 | — | — | US | claimed |
| CN-115516086-A | Compositions and methods for reducing allogeneic cell host rejection in apes ICP47 and variants | 南京传奇生物科技有限公司 | 2022-12-23 | — | — | CN | disclosed |
| CN-111978250-B | Fluorescent probe and application thereof in detecting hypochlorite | 中国科学院大连化学物理研究所 | 2022-12-13 | — | — | CN | disclosed |
| US-11207263-B2 | Cosmetic compositions | DOW SILICONES CORPORATION (US) | 2021-12-28 | — | — | US | disclosed |
| EP-3771336-A1 | REPELLENT COMPOSITION | Athenion AG (CH) | 2021-02-03 | — | — | EP | disclosed |
| WO-1995026329-A1 | NOVEL GLYCINE DERIVATIVES, INTERMEDIATES THEREFOR AND CLEANSER COMPOSITIONS COMPRISING THEM | KAO CORPORATION (JP) | 1995-10-05 | — | — | WO | disclosed |
| EP-0342056-B1 | Cosmetic composition | UNILEVER PLC (GB) | 1994-08-17 | — | — | EP | disclosed |
| US-4919846-A | Conditioning low skin sensitivity | SHISEIDO COMPANY LTD. (JP) | 1990-04-24 | — | — | US | disclosed |
| EP-0342056-A2 | Cosmetic composition | UNILEVER PLC (GB) | 1989-11-15 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200222302-A1 | FILM FORMING COMPOSITIONS HAVING A TACK-FREE SURFACE | C9, SCO2, H1-3 | ESR1 1756/4885CES2 1115/4885MEN1 2061/4885 |
| US-20200237639-A1 | COSMETIC COMPOSITIONS | H1-0, H1-3, HRH3 | ESR1 813/4885CES2 248/4885MEN1 1030/4885 |
| US-11207263-B2 | Cosmetic compositions | H1-0, H1-3, HRH3 | ESR1 902/4885CES2 156/4885MEN1 1880/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.