SCHEMBL326469

SCHEMBL326469

O=C(Oc1ccc(I)cc1)C(F)(F)F

nearest known ligand 0.44

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
ELANE P08246 11/20 0.44
TRPV1 Q8NER1 3/20 0.42
KIF11 P52732 1/20 0.38
APP P05067 1/20 0.37
TPMT P51580 1/20 0.37
CA1 P00915 1/20 0.36
CA2 P00918 1/20 0.36
CA9 Q16790 1/20 0.36
RXRA P19793 1/20 0.36
RXRB P28702 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Iodobenzene SCHEMBL10598814 0.83 GAA (0.46) ELANECA1CA2
SCHEMBL26343991 0.83 ELANE (0.53) ELANE
SCHEMBL24179235 0.82 ELANE (0.40) ELANETRPV1KIF11APPTPMT
SCHEMBL24361100 0.81 ELANE (0.39) ELANETRPV1KIF11APPTPMT
SCHEMBL2651602 0.81 ELANE (0.45) ELANEKIF11
SCHEMBL10738024 0.79 ELANE (0.56) ELANE
SCHEMBL9872338 0.79 LMNA (0.57) ELANECA2
SCHEMBL8538472 0.79 ELANE (0.44) ELANEKIF11
SCHEMBL16443964 0.79 ELANE (0.70) ELANE
SCHEMBL27746984 0.79 ELANE (0.48) ELANECA1CA2CA9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 136 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118108633-A Preparation method of L-glufosinate intermediate (S) -2- (((benzyloxy) carbonyl) amino) but-3-enoic acid methyl ester 浙江工业大学 2024-05-31 CN claimed
CN-118084706-A Synthesis method of 2- (4-hydroxyphenoxy) benzamide compound 河北科技大学 2024-05-28 CN claimed
CN-118026934-A N-azole-4-methylbenzenesulfonamide compound and preparation method and application thereof 安徽理工大学 2024-05-14 CN claimed
CN-117843600-A Fluorescent probe for detecting hypochlorous acid and preparation method and use method thereof 浙江理工大学 2024-04-09 CN claimed
CN-114539302-B P-type doped material based on triarylboron-nitrogen skeleton, and preparation method and application thereof 广东粤港澳大湾区黄埔材料研究院 2024-02-02 CN claimed
CN-117486968-A Preparation method of snake venom peptide 深圳创元生物医药科技有限公司 2024-02-02 CN claimed
CN-117466915-A Chromone-containing benzo [ d ] imidazo [2,1-b ] thiazole compound and preparation method and application thereof 江西科技师范大学 2024-01-30 CN claimed
CN-117304135-A Synthesis method of 4-substituted-5H-1, 2, 3-dithiazole-5-thione and derivative 衡阳师范学院 2023-12-29 CN claimed
CN-117164545-A Reversible fluorescent probe for detecting hypochlorous acid and preparation method and use method thereof 浙江理工大学 2023-12-05 CN claimed
CN-117126178-A Bisphenol thiazide compound and synthesis method thereof 湘潭大学 2023-11-28 CN claimed
CN-115286615-A Preparation method of racemic nicotine 深圳市真味生物科技有限公司 2022-11-04 CN claimed
CN-114539302-A P-type doped material based on triaryl boron-nitrogen framework and preparation method and application thereof 广东粤港澳大湾区黄埔材料研究院 2022-05-27 CN claimed
CN-113717033-A Benzyl ether compound and synthesis method thereof 嘉兴学院 2021-11-30 CN claimed
CN-113461469-A Thioether aromatic heterocyclic compound and preparation method and application thereof 广东工业大学 2021-10-01 CN claimed
CN-113416186-A Berberine hydrochloride dimer and preparation method and application thereof 北京大学深圳医院 2021-09-21 CN claimed
CN-109293692-B Gem-difluoroalkyl borate compounds and preparation method and application thereof 中山大学 2021-05-11 CN claimed
CN-110698322-B Synthesis method of coastal twinborn anthane diterpene Stemarin 浙江大学 2021-01-26 CN claimed
CN-110776442-A Preparation method of memantine hydrochloride intermediate 华中科技大学 2020-02-11 CN claimed
CN-110698322-A Synthesis method of coastal twinborn anthane diterpene Stemarin 浙江大学 2020-01-17 CN claimed
EP-0127235-B1 PARTIALLY RETRO-INVERTED DECAPEPTIDE AS A SPECIFIC RENIN INHIBITOR WITH HIGH RESISTANCE TO ENZYMATIC HYDROLYSIS ENI-Ente Nazionale Idrocarburi (IT) 1988-10-19 EP claimed