Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 5/20 | 0.56 |
| ▸ | CYP11B1 | P15538 | 5/20 | 0.45 |
| ▸ | CYP11B2 | P19099 | 4/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | PPARA | Q07869 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | LIPE | Q05469 | 2/20 | 0.42 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HTR2A | P28223 | 1/20 | 0.42 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26343991 | 0.83 | ELANE (0.53) | ELANEMEN1KMT2AMAPT | |
| SCHEMBL18726211 | 0.83 | ELANE (0.42) | ELANECYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL24901072 | 0.82 | ELANE (0.51) | ELANECYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL2651602 | 0.81 | ELANE (0.45) | ELANECYP1A2KMT2AHPGDSMN1; SMN2 | |
| SCHEMBL9486994 | 0.81 | ELANE (0.58) | ELANECYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL9872014 | 0.80 | KIF11 (0.43) | ELANECYP11B1CYP11B2MAPT | |
| SCHEMBL326469 | 0.79 | ELANE (0.44) | ELANE | |
| SCHEMBL8538472 | 0.79 | ELANE (0.44) | ELANEMEN1KMT2AMAPT | |
| SCHEMBL197454 | 0.79 | ELANE (0.83) | ELANECYP11B1CYP11B2CYP1A2CYP3A4 | |
| SCHEMBL9872338 | 0.79 | LMNA (0.57) | ELANECYP1A2MEN1KMT2ACYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4668830-A | Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-05-26 | — | — | US | claimed |
| US-4334111-A | PYROLYSIS OF PHENYL TRIHALOACETATE | THE DOW CHEMICAL COMPANY (US) | 1982-06-08 | — | — | US | claimed |
| US-12442289-B2 | Oil, gas and water well tracers with tunable release profile | SAUDI ARABIAN OIL COMPANY (SA) | 2025-10-14 | — | — | US | disclosed |
| US-20240318545-A1 | OIL, GAS AND WATER WELL TRACERS WITH TUNABLE RELEASE PROFILE | SAUDI ARABIAN OIL COMPANY (SA) | 2024-09-26 | — | — | US | disclosed |
| US-12037893-B2 | Oil, gas and water well tracers with tunable release profile | SAUDI ARABIAN OIL COMPANY (SA) | 2024-07-16 | — | — | US | disclosed |
| US-20240035374-A1 | OIL, GAS AND WATER WELL TRACERS WITH TUNABLE RELEASE PROFILE | ARAMCO SERVICES COMPANY (US) | 2024-02-01 | — | — | US | disclosed |
| CN-1859912-A | Inhibitors of Akt activity | SMITHKLINE BEECHAM CORP (US) | 2006-11-08 | — | — | CN | disclosed |
| US-4695657-A | Process for preparing compounds containing a difluoromethylene group in a position α to an oxygen atom | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-09-22 | — | — | US | disclosed |
| US-4668830-A | Process for the preparation of compounds containing a difluoromethylene or trifluoromethyl group | RHONE-POULENC SPECIALITES CHIMIQUES (FR) | 1987-05-26 | — | — | US | disclosed |