Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 8/20 | 0.44 |
| ▸ | LDHA | P00338 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MGLL | Q99685 | 1/20 | 0.39 |
| ▸ | CHRNA7 | P36544 | 1/20 | 0.38 |
| ▸ | CES2 | O00748 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26343991 | 0.83 | ELANE (0.53) | ELANEMAPTMEN1KMT2A | |
| SCHEMBL2651602 | 0.81 | ELANE (0.45) | ELANEKMT2AALDH1A1CES2CES1 | |
| SCHEMBL27746984 | 0.79 | ELANE (0.48) | ELANELMNAALDH1A1CES2CES1 | |
| SCHEMBL326469 | 0.79 | ELANE (0.44) | ELANEKIF11 | |
| SCHEMBL11227350 | 0.79 | ELANE (0.44) | ELANELDHAMAPTMEN1LMNA | |
| SCHEMBL10738024 | 0.79 | ELANE (0.56) | ELANEMAPTMEN1KMT2A | |
| SCHEMBL9872338 | 0.79 | LMNA (0.57) | ELANEMEN1LMNAKMT2ANPSR1 | |
| SCHEMBL6024356 | 0.79 | ELANE (0.70) | ELANELDHAMAPTMEN1LMNA | |
| SCHEMBL1255890 | 0.78 | ELANE (0.47) | ELANEMAPTALDH1A1L3MBTL1CES1 | |
| SCHEMBL15499305 | 0.78 | KMT2A (0.49) | ELANEMAPTMEN1LMNAKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5730904-A | Partially fluroinated benzene derivatives, and liquid-crystalline medium | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1998-03-24 | — | — | US | disclosed |
| EP-0002906-B1 | NOVEL PERIMIDINES, THEIR PREPARATION, FORMULATIONS AND USE AS IMMUNOSUPPRESSIVES | ELI LILLY AND COMPANY (US) | 1982-04-14 | — | — | EP | disclosed |
| US-4294964-A | IMMUNOSUPRESSIVE AGENTS | ELI LILLY AND COMPANY (US) | 1981-10-13 | — | — | US | disclosed |
| US-4224326-A | 2-ARYL-1H-PERIMIDINES | ELI LILLY AND COMPANY (US) | 1980-09-23 | — | — | US | disclosed |
| EP-0002906-A2 | Novel perimidines, their preparation, formulations and use as immunosuppressives | ELI LILLY AND COMPANY (US) | 1979-07-11 | — | — | EP | disclosed |