SCHEMBL3264875

SCHEMBL3264875

Cn1oc(=O)nc1N(Cc1cnc(Cl)s1)C1CC1

nearest known ligand 0.39

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.39
LMNA P02545 1/20 0.36
GAA P10253 1/20 0.36
BRD4 O60885 1/20 0.31
ADCY10 Q96PN6 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL231942 0.79 ALDH1A1 (0.37) ALDH1A1
SCHEMBL3264884 0.65 PARG (0.34) ALDH1A1LMNAGAA
SCHEMBL13223227 0.62 KMT2A (0.44) ALDH1A1LMNAGAA
SCHEMBL12949772 0.60 LMNA (0.34) ALDH1A1LMNAGAA
SCHEMBL19672954 0.59 KMT2A (0.42) ALDH1A1LMNAGAA
SCHEMBL3091812 0.58 CRHR1 (0.43) ALDH1A1LMNAGAA
SCHEMBL14101263 0.57 LMNA (0.34) ALDH1A1LMNAGAA
SCHEMBL229674 0.57 LMNA (0.34) ALDH1A1LMNAGAA
SCHEMBL15296925 0.57 L3MBTL1 (0.43) ALDH1A1LMNAGAA
SCHEMBL10028749 0.56 KMT2A (0.36) ALDH1A1LMNAGAA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010005692-A2 INSECTICIDAL CYCLIC CARBONYL AMIDINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-01-14 WO claimed
WO-2010005692-A2 INSECTICIDAL CYCLIC CARBONYL AMIDINES E. I. DU PONT DE NEMOURS AND COMPANY (US) 2010-01-14 WO disclosed