Dl-Phenylalanine

Dl-Phenylalanine

SCHEMBL28464461

CC(N)C(=O)O.NC(Cc1ccccc1)C(=O)O.Nc1ccc([N+](=O)[O-])cc1

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SLC7A5 Q01650 2/20 0.56
ALPI P09923 1/20 0.56
PKM P14618 1/20 0.56
PTGS1 P23219 1/20 0.56
XIAP P98170 1/20 0.56
NPC1 O15118 2/20 0.52
RAB9A P51151 2/20 0.52
TP53 P04637 1/20 0.52
SMN1; SMN2 Q16637 1/20 0.52
MEN1 O00255 1/20 0.51
KMT2A Q03164 1/20 0.51
MMP2 P08253 1/20 0.51
MC4R P32245 1/20 0.48
MAPT P10636 1/20 0.47
ANPEP P15144 1/20 0.47
ERAP2 Q6P179 1/20 0.47
ERAP1 Q9NZ08 1/20 0.47
ALDH1A1 P00352 2/20 0.46
CRHBP P24387 1/20 0.46
CRHR2 Q13324 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Dl-Phenylalanine SCHEMBL5582272 0.95 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL2544094 0.95 SLC7A5 (0.63) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL27740947 0.93 SLC7A5 (0.61) SLC7A5ALPIPKMPTGS1XIAP
Dl-Phenylalanine SCHEMBL28184207 0.91 SLC7A5 (0.52) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL8981660 0.85 DPP4 (0.41) SLC7A5ALPIPKMPTGS1XIAP
Phenylalanine SCHEMBL3431329 0.85 DPP4 (0.41) SLC7A5ALPIPKMPTGS1XIAP
4-Nitroaniline SCHEMBL3264892 0.85 ALDH1A1 (0.64) PKMNPC1SMN1; SMN2MEN1KMT2A
4-Nitroaniline SCHEMBL10711921 0.85 ALDH1A1 (0.64) PKMNPC1SMN1; SMN2MEN1KMT2A
4-Nitroaniline SCHEMBL3264895 0.85 ALDH1A1 (0.64) PKMNPC1SMN1; SMN2MEN1KMT2A
4-Nitroaniline SCHEMBL5974424 0.85 ALDH1A1 (0.64) PKMNPC1SMN1; SMN2MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-105683380-B Increasing transgene expression in eukaryotic cells by reducing RNA interference 丹尼斯科美国公司 2020-07-03 CN disclosed