Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | HMGCR | P04035 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.37 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | BLM | P54132 | 1/20 | 0.37 |
| ▸ | CASP7 | P55210 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.37 |
| ▸ | GABBR2 | O75899 | 1/20 | 0.36 |
| ▸ | GABBR1 | Q9UBS5 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.33 |
| ▸ | RXRA | P19793 | 1/20 | 0.32 |
| ▸ | RXRB | P28702 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3201259 | 1.00 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL2032568 | 1.00 | GABRA1 (0.39) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL189788 | 0.91 | GABRA1 (0.46) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL14005550 | 0.91 | GABRA1 (0.40) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL2033311 | 0.88 | HMGCR (0.32) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL2033312 | 0.88 | HMGCR (0.32) | GABRA1GABRB2HMGCRMAPTTP53 | |
| SCHEMBL10024117 | 0.83 | CYP1A2 (0.53) | MAPTTP53MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL10024113 | 0.83 | CYP1A2 (0.53) | MAPTTP53MAPK1SMN1; SMN2CYP1A2 | |
| SCHEMBL6573320 | 0.82 | TP53 (0.46) | GABRA1GABRB2MAPTTP53CYP3A4 | |
| SCHEMBL6573201 | 0.82 | TP53 (0.46) | GABRA1GABRB2MAPTTP53CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7682708-B2 | Dendrimers | ISIS INNOVATION LIMITED (GB) | 2010-03-23 | — | — | US | disclosed |
| US-20080004471-A1 | Dendrimers | OXFORD UNIVERSITY INNOVATION LIMITED (GB) | 2008-01-03 | — | — | US | disclosed |
| EP-1027398-B1 | LIGHT-EMITTING DENDRIMERS AND DEVICES | ISIS INNOVATION (GB) | 2004-06-09 | — | — | EP | disclosed |
| US-6720093-B2 | DEVICE INCORPORATING AS, OR IN, ITS LIGHT-EMITTING ELEMENT LUMINESCENT COMPOUND INCLUDING CONJUGATED DENDRITIC MOLECULAR STRUCTURE COMPRISING GROUPS SELECTED FROM ARYL AND HETEROARYL GROUPS AND ALKENYL GROUPS CONNECTED TO EACH OTHER | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2004-04-13 | — | — | US | disclosed |
| US-20030165716-A1 | Dendrimers according to present invention which can be used for incorporation into light emitting devices have core and/or branches comprising electroluminescent or charge-transporting chromophores (conjugated units) | CAMBRIDGE DISPLAY TECHNOLOGY LIMITED (GB) | 2003-09-04 | — | — | US | disclosed |
| US-6558818-B1 | Light-emitting dendrimers and devices | ISIS INNOVATION LTD. (GB) | 2003-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030165716-A1 | Dendrimers according to present invention which can be used for incorporation into light emitting devices have core and/or branches comprising electroluminescent or charge-transporting chromophores (conjugated units) | CLTB, CLTA, CLTC | GABRA1 1200/4885GABRB2 763/4885HMGCR 4079/4885 |
| US-20080004471-A1 | Dendrimers | NPY1R, CHRM1, TLR1 | GABRA1 1293/4885GABRB2 1652/4885HMGCR 4158/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.