SCHEMBL189788

SCHEMBL189788

CC(C)(C)c1cc(C=O)cc(C(C)(C)C)c1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GABRA1 P14867 1/20 0.46
GABRB2 P47870 1/20 0.46
HMGCR P04035 1/20 0.42
POLB P06746 1/20 0.37
MAPT P10636 2/20 0.37
TP53 P04637 1/20 0.37
CYP3A4 P08684 1/20 0.37
ALOX15 P16050 1/20 0.37
MAPK1 P28482 1/20 0.37
BLM P54132 1/20 0.37
CASP7 P55210 1/20 0.37
SMN1; SMN2 Q16637 1/20 0.37
HSD17B10 Q99714 1/20 0.37
TDP1 Q9NUW8 1/20 0.37
RXRB P28702 5/20 0.36
RXRA P19793 4/20 0.36
RXRG P48443 3/20 0.36
EPHX2 P34913 1/20 0.36
NR1H4 Q96RI1 1/20 0.36
CYP2A6 P11509 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL14005550 0.95 GABRA1 (0.40) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL3264978 0.91 GABRA1 (0.39) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL2032568 0.91 GABRA1 (0.39) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL3201259 0.91 GABRA1 (0.39) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL16024474 0.89 GABRA1 (0.43) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL8008577 0.86 RXRA (0.40) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL29727683 0.86 RXRB (0.44) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL23801982 0.85 GABRA1 (0.35) GABRA1GABRB2HMGCRMAPTTP53
SCHEMBL1726479 0.84 GABRA1 (0.33) GABRA1GABRB2HMGCRPOLBMAPT
SCHEMBL1542624 0.84 ALDH1A1 (0.42) GABRA1GABRB2HMGCRPOLBSMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 510 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122037723-A Hydrophobic heat insulation material containing aerogel additive and preparation method thereof 赢胜节能集团股份有限公司 2026-05-15 CN claimed
CN-119638727-A Terpyridyl zinc complex and preparation method and application thereof 中南大学 2025-03-18 CN claimed
CN-116836190-A Dipyrromethene fluorescent dye containing 3, 5-di-tert-butyl 福州大学 2023-10-03 CN claimed
CN-114950159-B Preparation method of aromatic polymer separation membrane based on super acid catalysis 南京工业大学 2023-06-06 CN claimed
CN-114950159-A Preparation method of aromatic polymer separation membrane based on super-acid catalysis preparation 南京工业大学 2022-08-30 CN claimed
CN-113549062-B Chiral quaternary ammonium salt phase transfer catalyst with high steric hindrance derived from cinchona alkaloid and synthesis method thereof 南京工业大学 2022-08-09 CN claimed
CN-112094277-B Triple fused porphyrin dimer covalent functionalized single-walled carbon nanotube nonlinear nano hybrid material and preparation thereof 同济大学 2021-10-08 CN claimed
CN-111825684-B Modifiable hyperconjugated triple fused porphyrin dimer strong two-photon absorption material and preparation thereof 同济大学 2021-10-08 CN claimed
CN-109575275-B High-solubility polyaramid containing di-tert-butyl benzene and dimethyl structure simultaneously and preparation method and application thereof 常州大学 2021-01-29 CN claimed
CN-112094277-A Triple fused porphyrin dimer covalent functionalized single-walled carbon nanotube nonlinear nano hybrid material and preparation thereof 同济大学 2020-12-18 CN claimed
CN-103962180-B For the preparation of the Salen coordination polymer Catalysts and its preparation method of alpha-aminonitriles SHANTOU UNIV. (CN) 2016-02-17 CN claimed
CN-105254639-A Serial compounds with triptycene as framework and in bridge connection with metalloporphyrin through pyrene tetrone and preparation method therefor BEIJING INST TECHNOLOGY 2016-01-20 CN claimed
EP-2895456-A1 AMINOETHYLATION PROCESS FOR PRODUCING ARYLOXYALKYLENE AMINE COMPOUNDS Chevron Oronite Company LLC (US) 2015-07-22 EP claimed
CN-104650103-A Pyrene tetrone bridging molecular tweezers-series metalloporphyrin compound and preparation method thereof BEIJING INST TECHNOLOGY 2015-05-27 CN claimed
US-9035097-B2 Aminoethylation process having improved yield of aryloxyalkylene amine compounds and reduced urea by-products CHEVRON ORONITE COMPANY LLC (US) 2015-05-19 US claimed
CN-103962180-A Salen coordination polymer catalyst for preparing alpha-aminonitrile and preparation method of catalyst UNIV SHANTOU 2014-08-06 CN claimed
CN-103664687-A Synthesis method of 2-((3,5-di-tertiary butyl benzal) amino) - 4 - methyl pentanoic acid XUZHOU RUISAI TECHNOLOGY IND CO LTD 2014-03-26 CN claimed
WO-2014042756-A1 AMINOETHYLATION PROCESS FOR PRODUCING ARYLOXYALKYLENE AMINE COMPOUNDS CHEVRON ORONITE COMPANY LLC (US) 2014-03-20 WO claimed
US-20140073814-A1 AMINOETHYLATION PROCESS HAVING IMPROVED YIELD OF ARYLOXYALKYLENE AMINE COMPOUNDS AND REDUCED UREA BY-PRODUCTS CHEVRON ORONITE COMPANY LLC (US) 2014-03-13 US claimed
EP-0057882-B1 3,5-DI-TERT-BUTYLSTYRENE DERIVATIVES, PROCESSES FOR THEIR PREPARATIONS, AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM KANEGAFUCHI KAGAKU KOGYO KABUSHIKI KAISHA (JP) 1986-04-02 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20140073814-A1 AMINOETHYLATION PROCESS HAVING IMPROVED YIELD OF ARYLOXYALKYLENE AMINE COMPOUNDS AND REDUCED UREA BY-PRODUCTS SRM, ODC1, DDC GABRA1 2336/4885GABRB2 1357/4885HMGCR 3783/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.