Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.53 |
| ▸ | CA12 | O43570 | 1/20 | 0.51 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | CA9 | Q16790 | 1/20 | 0.51 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CD274 | Q9NZQ7 | 2/20 | 0.50 |
| ▸ | LMNA | P02545 | 2/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | CNR1 | P21554 | 1/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | HTR1A | P08908 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
| ▸ | GLA | P06280 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL166433 | 0.93 | TDP1 (0.58) | TDP1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL5657522 | 0.91 | GLA (0.58) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL16932573 | 0.86 | SMN1; SMN2 (0.51) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL76649 | 0.82 | GAA (0.68) | POLBLMNAHPGDSMN1; SMN2TSHR | |
| Formic Acid SCHEMBL6624948 | 0.82 | TSHR (0.54) | TDP1POLBSMN1; SMN2TSHRALDH1A1 | |
| SCHEMBL14562644 | 0.81 | MAPK1 (0.56) | TDP1CA12CA1CA2CA9 | |
| Hydrochloric Acid SCHEMBL5658003 | 0.81 | GAA (0.66) | POLBLMNAHPGDSMN1; SMN2TSHR | |
| Cyclohexanol SCHEMBL9499559 | 0.80 | EPHX1 (0.52) | TDP1TSHRALDH1A1 | |
| SCHEMBL3897267 | 0.80 | SMN1; SMN2 (0.60) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL14237141 | 0.80 | TDP1 (0.60) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011819-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |