Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.54 |
| ▸ | CA12 | O43570 | 1/20 | 0.49 |
| ▸ | CA1 | P00915 | 1/20 | 0.49 |
| ▸ | CA2 | P00918 | 1/20 | 0.49 |
| ▸ | CA9 | Q16790 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.47 |
| ▸ | MAOA | P21397 | 1/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | CD274 | Q9NZQ7 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12331329 | 0.83 | TDP1 (0.56) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL12233401 | 0.81 | TDP1 (0.67) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL14562644 | 0.78 | MAPK1 (0.56) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL20123385 | 0.77 | TDP1 (0.54) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL2759481 | 0.77 | TDP1 (0.57) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL3897267 | 0.77 | SMN1; SMN2 (0.60) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL30522606 | 0.77 | TDP1 (0.75) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL14237141 | 0.77 | TDP1 (0.60) | TDP1CA12CA1CA2CA9 | |
| Formic Acid SCHEMBL3265060 | 0.77 | TDP1 (0.53) | TDP1CA12CA1CA2CA9 | |
| SCHEMBL39934 | 0.76 | CD274 (0.60) | TDP1CA12CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010011819-A1 | CHEMICAL COMPOUNDS | SMITHKLINE BEECHAM CORPORATION (US) | 2010-01-28 | — | — | WO | disclosed |