Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.45 |
| ▸ | RECQL | P46063 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 4/20 | 0.38 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2563782 | 0.76 | KMT2A (0.50) | MEN1KMT2AALDH1A1RECQLHPGD | |
| SCHEMBL5376580 | 0.74 | NUDT1 (0.41) | ALDH1A1HPGDMAPTPOLBL3MBTL1 | |
| SCHEMBL13736844 | 0.74 | SCN9A (0.47) | CYP1A2CYP3A4CYP2C9CYP2C19RAB9A | |
| SCHEMBL13134192 | 0.73 | — | — | |
| SCHEMBL17574489 | 0.73 | MEN1 (0.43) | MEN1KMT2AALDH1A1RECQLHPGD | |
| SCHEMBL2053065 | 0.71 | ALDH1A1 (0.47) | MEN1KMT2AALDH1A1HPGDTP53 | |
| SCHEMBL13134199 | 0.70 | EGFR (0.31) | — | |
| SCHEMBL18785373 | 0.70 | METAP2 (0.38) | HPGD | |
| SCHEMBL11034285 | 0.70 | ALDH1A1 (0.32) | MEN1KMT2AALDH1A1HPGDTP53 | |
| SCHEMBL3264806 | 0.68 | ALDH1A1 (0.34) | MEN1KMT2AALDH1A1MAPTPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7691635-B2 | Labeling reagents, methods for the synthesis of such reagents and methods for the detection of biological molecules | BIOMERIEUX (FR) | 2010-04-06 | — | — | US | disclosed |
| EP-1383732-B1 | LABELLING REAGENTS, METHOD FOR SYNTHESIS OF SAID REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES | BIO MERIEUX (FR) | 2010-02-17 | — | — | EP | disclosed |
| US-7338805-B2 | Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules | BIO MERIEUX (FR) | 2008-03-04 | — | — | US | disclosed |
| US-20080032288-A1 | Labeling Reagents, Methods for the Synthesis of Such Reagents and Methods for the Detection of Biological Molecules | BIOMERIEUX (FR) | 2008-02-07 | — | — | US | disclosed |
| EP-1727825-A1 | LABELLING REAGENTS, METHODS FOR THE SYNTHESIS OF SUCH REAGENTS AND METHODS FOR THE DETECTION OF BIOLOGICAL MOLECULES | BIOMERIEUX (FR) | 2006-12-06 | — | — | EP | disclosed |
| EP-1383925-B1 | METHOD FOR LABELLING AND FRAGMENTING DNA | BIO MERIEUX (FR) | 2006-09-20 | — | — | EP | disclosed |
| US-7060441-B2 | Method for fragmenting and labeling DNA involving abasic sites and phosphate labeling | BIOMERIEUX (FR) | 2006-06-13 | — | — | US | disclosed |
| WO-2005092910-A1 | LABELLING REAGENTS, METHODS FOR THE SYNTHESIS OF SUCH REAGENTS AND METHODS FOR THE DETECTION OF BIOLOGICAL MOLECULES | BIOMERIEUX (FR) | 2005-10-06 | — | — | WO | disclosed |
| EP-1383925-A2 | METHOD FOR LABELLING AND FRAGMENTING DNA | BIO MERIEUX (FR) | 2004-01-28 | — | — | EP | disclosed |
| EP-1383732-A1 | LABELLING REAGENTS, METHOD FOR SYNTHESIS OF SAID REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES | BIO MERIEUX (FR) | 2004-01-28 | — | — | EP | disclosed |
| US-20030186448-A1 | Labeling reagents, methods for synthesizing such reagents and methods for detecting biological molecules | BIO MERIEUX (FR) | 2003-10-02 | — | — | US | disclosed |
| US-20030143555-A1 | Fragmenting the DNA by creating at least one abasic site on DNA, attaching a marker to one of the fragments by means of labeling reagent which is covalently and predominantly coupling to the phosphate of the fragment | BIO MERIEUX (FR) | 2003-07-31 | — | — | US | disclosed |
| WO-2002090319-A1 | LABELLING REAGENTS, METHOD FOR SYNTHESIS OF SAID REAGENTS AND METHODS FOR DETECTING BIOLOGICAL MOLECULES | BIO MERIEUX (FR) | 2002-11-14 | — | — | WO | disclosed |
| WO-2002090584-A2 | METHOD FOR LABELLING AND FRAGMENTING DNA | BIO MERIEUX (FR) | 2002-11-14 | — | — | WO | disclosed |
| US-6103737-A | Aryl- and arylamino- substituted heterocycles as corticotropin releasing hormone antagonists | DUPONT PHARMACEUTICALS COMPANY (US) | 2000-08-15 | — | — | US | disclosed |
| EP-0994860-A1 | ARYL-AND ARYLAMINO-SUBSTITUTED HETEROCYCLES AS CORTICOTROPIN RELEASING HORMONE ANTAGONISTS | Du Pont Pharmaceuticals Company (US) | 2000-04-26 | — | — | EP | disclosed |
| WO-1999001439-A1 | ARYL-AND ARYLAMINO-SUBSTITUTED HETEROCYCLES AS CORTICOTROPIN RELEASING HORMONE ANTAGONISTS | DU PONT PHARMACEUTICALS COMPANY (US) | 1999-01-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080032288-A1 | Labeling Reagents, Methods for the Synthesis of Such Reagents and Methods for the Detection of Biological Molecules | CBR3, CBR1, NR4A1 | MEN1 2676/4885KMT2A 1708/4885ALDH1A1 1817/4885 |
| US-20030143555-A1 | Fragmenting the DNA by creating at least one abasic site on DNA, attaching a marker to one of the fragments by means of labeling reagent which is covalently and predominantly coupling to the phosphate of the fragment | FEN1, DNMT1, UNG | MEN1 3188/4885KMT2A 2298/4885ALDH1A1 1360/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.