Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.44 |
| ▸ | CSGALNACT1 | Q8TDX6 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.41 |
| ▸ | MTOR | P42345 | 1/20 | 0.41 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3266083 | 0.84 | CSGALNACT1 (0.51) | KDM4ECSGALNACT1SMN1; SMN2MAPTPIK3CA | |
| SCHEMBL3265094 | 0.83 | KDM4E (0.52) | KDM4EGAASCN10ASMN1; SMN2TP53 | |
| SCHEMBL2296375 | 0.79 | CSGALNACT1 (0.65) | CSGALNACT1 | |
| SCHEMBL3265779 | 0.79 | KDM4E (0.46) | KDM4EGAATP53MAPTNPC1 | |
| SCHEMBL2296367 | 0.79 | CSGALNACT1 (0.65) | CSGALNACT1 | |
| SCHEMBL3265444 | 0.77 | CSGALNACT1 (0.54) | CSGALNACT1SMN1; SMN2MAPTLMNATSHR | |
| SCHEMBL2296821 | 0.76 | CSGALNACT1 (0.53) | SCN10ACSGALNACT1SMN1; SMN2TP53MAPT | |
| SCHEMBL2296824 | 0.76 | CSGALNACT1 (0.53) | SCN10ACSGALNACT1SMN1; SMN2TP53MAPT | |
| SCHEMBL2299081 | 0.72 | DGAT1 (0.56) | CSGALNACT1 | |
| SCHEMBL2299953 | 0.70 | CSGALNACT1 (0.66) | CSGALNACT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | claimed |