Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSGALNACT1 | Q8TDX6 | 4/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 4/20 | 0.47 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | DGAT1 | O75907 | 3/20 | 0.46 |
| ▸ | HTT | P42858 | 2/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | KLK7 | P49862 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA9 | Q16790 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3265449 | 0.84 | KDM4E (0.44) | CSGALNACT1PIK3CAMTORPIK3CGNPC1 | |
| SCHEMBL2298388 | 0.82 | CSGALNACT1 (0.71) | CSGALNACT1DGAT1 | |
| SCHEMBL2299047 | 0.80 | CSGALNACT1 (0.60) | CSGALNACT1PIK3CAMTORPIK3CGNPC1 | |
| SCHEMBL3266079 | 0.80 | CSGALNACT1 (0.60) | CSGALNACT1PIK3CAMTORPIK3CGNPC1 | |
| SCHEMBL3265094 | 0.76 | KDM4E (0.52) | SMN1; SMN2LMNAMAPTKDM4E | |
| SCHEMBL3265779 | 0.73 | KDM4E (0.46) | NPC1RAB9ALMNAMAPTHTT | |
| SCHEMBL3089092 | 0.72 | SMN1; SMN2 (0.59) | CSGALNACT1PIK3CAMTORPIK3CGNPC1 | |
| SCHEMBL2299944 | 0.72 | CSGALNACT1 (0.66) | CSGALNACT1DGAT1 | |
| SCHEMBL2299953 | 0.72 | CSGALNACT1 (0.66) | CSGALNACT1DGAT1 | |
| SCHEMBL2298368 | 0.71 | DGAT1 (0.62) | CSGALNACT1DGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010023609-A1 | OXAZOLE, OXADIAZOLE AND THIAZOLE DERIVATIVES AS DIACYLGLYCEROL ACYLTRANFERASE INHIBITORS | PIRAMAL LIFE SCIENCES LIMITED (IN) | 2010-03-04 | — | — | WO | disclosed |