SCHEMBL3265488

SCHEMBL3265488

CCCc1cccc(N2CCC(CCNC(=O)OCC(=O)NC)CC2)n1

nearest known ligand 0.40

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FAAH O00519 1/20 0.40
AOC3 Q16853 1/20 0.39
CHRM4 P08173 4/20 0.38
TPSAB1 Q15661 1/20 0.37
TPSD1 Q9BZJ3 1/20 0.37
TPSG1 Q9NRR2 1/20 0.37
ACACB O00763 2/20 0.37
MAP4K4 O95819 1/20 0.36
ACACA Q13085 1/20 0.36
CKS1B P61024 4/20 0.36
SKP1 P63208 4/20 0.36
SKP2 Q13309 4/20 0.36
SUV39H2 Q9H5I1 2/20 0.36
HRH3 Q9Y5N1 3/20 0.36
PKM P14618 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL240061 0.88 HRH3 (0.39) FAAHAOC3CHRM4TPSAB1TPSD1
SCHEMBL3268986 0.88 HSD11B1 (0.41) FAAHCHRM4TPSAB1TPSD1TPSG1
SCHEMBL240877 0.87 TGM2 (0.44) FAAHCHRM4ACACBMAP4K4ACACA
SCHEMBL29489154 0.87 TGM2 (0.44) FAAHCHRM4ACACBMAP4K4ACACA
Hydrochloric Acid SCHEMBL238862 0.86 TGM2 (0.43) FAAHCHRM4ACACBMAP4K4ACACA
SCHEMBL3266800 0.85 ACACB (0.40) FAAHCHRM4TPSAB1TPSD1TPSG1
SCHEMBL3265570 0.83 ACACB (0.42) FAAHCHRM4ACACBMAP4K4SUV39H2
SCHEMBL1729627 0.83 CHRM4 (0.43) AOC3CHRM4ACACBCKS1BSKP1
SCHEMBL3266796 0.82 CHRM4 (0.48) FAAHCHRM4HRH3
SCHEMBL241775 0.81 ACACB (0.44) ACACBMAP4K4ACACA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20120004207-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES SANOFI-AVENTIS (FR) 2012-01-05 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20120004207-A1 THERAPEUTIC USES OF DERIVATIVES OF PIPERIDINYL-AND PIPERIDINYL-ALKYL CARBAMATES CLCN2, CLIC1, H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 FAAH 361/4885AOC3 167/4885CHRM4 243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.