SCHEMBL3265568

SCHEMBL3265568

ClC(Cl)(Cl)c1ncncn1.FC(F)(F)c1cccc(C(Cl)(Cl)Cl)c1

nearest known ligand 0.41

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.39
MAPK1 P28482 1/20 0.39
CYP19A1 P11511 1/20 0.38
SYK P43405 1/20 0.36
KIF11 P52732 1/20 0.36
THRB P10828 1/20 0.36
CES2 O00748 1/20 0.36
MGLL Q99685 1/20 0.36
SCN2A Q99250 1/20 0.36
KDM4E B2RXH2 1/20 0.35
KMO O15229 1/20 0.35
CTSC P53634 1/20 0.35
PNMT P11086 1/20 0.35
ALDH1A1 P00352 1/20 0.35
EGFR P00533 1/20 0.35
ABCG2 Q9UNQ0 1/20 0.35
TAAR1 Q96RJ0 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7759984 0.82 TSHR (0.54) TSHRMAPK1KIF11CES2MGLL
SCHEMBL2464063 0.81 CYP19A1 (0.42) TSHRMAPK1CYP19A1KIF11ALDH1A1
SCHEMBL5447490 0.80 ACHE (0.35) TSHRMAPK1KIF11ALDH1A1
SCHEMBL607283 0.78 TSHR (0.58) TSHRMAPK1CYP19A1ALDH1A1EGFR
SCHEMBL2454679 0.76 GRM5 (0.40) TSHRKIF11ABCG2
SCHEMBL2865073 0.76 CLK4 (0.38) TSHRMAPK1KIF11KDM4EALDH1A1
SCHEMBL3208807 0.73 PTPN1 (0.37) TSHRCYP19A1KDM4EALDH1A1EGFR
SCHEMBL251722 0.73 HSP90AA1 (0.38)
SCHEMBL1538783 0.72 MAOB (0.50) TSHRMAPK1KIF11THRBCES2
SCHEMBL10894279 0.72 TSHR (0.44) TSHRMAPK1KIF11CES2MGLL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1695822-B1 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORP (JP) 2010-05-12 EP disclosed
US-7704671-B2 comprising hydrophilic support, undercoat layer and laser-sensitive photopolymerizable layer, wherein undercoat layer contains copolymer containing a repeating unit having at least one ethylenically unsaturated bond and repeating unit having functional group capable of interacting with surface of support FUJIFILM CORPORATION (JP) 2010-04-27 US disclosed
US-7300740-B2 Lithographic printing plate precursor and lithographic printing method FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
US-20070072116-A1 comprising hydrophilic support, undercoat layer and laser-sensitive photopolymerizable layer, wherein undercoat layer contains copolymer containing a repeating unit having at least one ethylenically unsaturated bond and repeating unit having functional group capable of interacting with surface of support FUJI PHOTO FILM CO., LTD. 2007-03-29 US disclosed
EP-1767352-A2 Lithographic printing plate precursor and lithographic printing method FUJIFILM Corporation (JP) 2007-03-28 EP disclosed
US-20060194149-A1 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. 2006-08-31 US disclosed
EP-1695822-A2 Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO., LTD. (JP) 2006-08-30 EP disclosed