Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.58 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | KCNN4 | O15554 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.31 |
| ▸ | CCNE2 | O96020 | 1/20 | 0.31 |
| ▸ | CDK1 | P06493 | 1/20 | 0.31 |
| ▸ | CDK4 | P11802 | 1/20 | 0.31 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.31 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.31 |
| ▸ | CCND1 | P24385 | 1/20 | 0.31 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.31 |
| ▸ | CDK2 | P24941 | 1/20 | 0.31 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.31 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.31 |
| ▸ | CYP19A1 | P11511 | 4/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.30 |
| ▸ | NR1I2 | O75469 | 1/20 | 0.30 |
| ▸ | GMNN | O75496 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL251722 | 0.82 | HSP90AA1 (0.38) | — | |
| SCHEMBL2464063 | 0.80 | CYP19A1 (0.42) | TSHRCYP1A2ALDH1A1CYP19A1USP2 | |
| SCHEMBL5447490 | 0.78 | ACHE (0.35) | TSHRCYP1A2ALDH1A1LMNACYP3A4 | |
| SCHEMBL3208807 | 0.78 | PTPN1 (0.37) | TSHRCYP1A2ALDH1A1CYP19A1EGFR | |
| SCHEMBL3265568 | 0.78 | TSHR (0.39) | TSHRALDH1A1CYP19A1EGFRMAPK1 | |
| Disulfone SCHEMBL28896701 | 0.77 | ALDH1A1 (0.42) | TSHRALDH1A1CA2LMNACYP3A4 | |
| SCHEMBL522316 | 0.76 | TSHR (1.00) | TSHRCYP1A2KCNN4ALDH1A1LMNA | |
| SCHEMBL29126179 | 0.76 | KCNN4 (0.35) | TSHRKCNN4ALDH1A1CYP19A1EGFR | |
| SCHEMBL2865073 | 0.75 | CLK4 (0.38) | TSHRCYP1A2ALDH1A1MEN1USP2 | |
| SCHEMBL2454679 | 0.75 | GRM5 (0.40) | TSHRCYP1A2CYP3A4CYP2D6DRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8113116-B2 | Lithographic printing plate precursor | FUJIFILM CORPORATION (JP) | 2012-02-14 | — | — | US | disclosed |
| US-20080070998-A1 | Foam Production Method | OJI PAPER CO., LTD. (JP) | 2008-03-20 | — | — | US | disclosed |
| US-20070214987-A1 | Lithographic printing plate precursor | FUJIFILM CORPORATION | 2007-09-20 | — | — | US | disclosed |