⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1497520 | 0.71 | TSHR (0.41) | — | |
| SCHEMBL2334872 | 0.69 | — | — | |
| SCHEMBL7177724 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL7549527 | 0.67 | TSHR (0.43) | — | |
| SCHEMBL11070461 | 0.67 | ALDH1A1 (0.35) | — | |
| SCHEMBL20656 | 0.67 | TSHR (0.43) | — | |
| Formaldehyde SCHEMBL11036055 | 0.65 | PYCR1 (0.41) | — | |
| SCHEMBL324883 | 0.65 | — | — | |
| SCHEMBL24833 | 0.65 | — | — | |
| SCHEMBL2417531 | 0.64 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 71 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1736052-B1 | Stem/leaf desiccant | SUMITOMO CHEMICAL CO (JP) | 2010-04-21 | — | — | EP | claimed |
| US-20090264412-A1 | Combination Therapy Using An 11beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor And A Glucocorticoid Receptor Agonist To Minimize The Side Effects Associated With Glucocorticoid Receptor Agonist Therapy | HIGH POINT PHARMACEUTICALS, LLC (US) | 2009-10-22 | — | — | US | claimed |
| US-20090137574-A1 | Combination Therapy Using an 11Beta-Hydroxysteroid Dehydrogenase Type 1 Inhibitor and an Antihypertensive Agent for the Treatment of Metabolic Syndrome and Related Diseases and Disorders | NOVO NORDISK A/S (DK) | 2009-05-28 | — | — | US | claimed |
| US-20070270408-A1 | Pharmaceutical use of substituted pyrazolo[1,5-a]pyrimidines | NOVO NORDISK A/S (DK) | 2007-11-22 | — | — | US | claimed |
| EP-1782859-A2 | Pharmaceutical use of substituted pyrazolo [1,5- a]pyrimidines | NOVO NORDISK A/S (DK) | 2007-05-09 | — | — | EP | claimed |
| EP-1397958-B1 | STEM/LEAF DESICCANT | SUMITOMO CHEMICAL CO (JP) | 2007-01-10 | — | — | EP | claimed |
| EP-1342735-B1 | Process for the production of high-solids coatings resins via controlled radical polymerisation | ARKEMA INC (US) | 2006-12-20 | — | — | EP | claimed |
| US-20060111348-A1 | Combination therapy using an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and an antihypertensive agent for the treatment of metabolic syndrome and related diseases and disorders | NOVO NORDISK A/S (DK) | 2006-05-25 | — | — | US | claimed |
| US-20060094699-A1 | Combination therapy using an 11beta-hydroxysteroid dehydrogenase type 1 inhibitor and a glucocorticoid receptor agonist to minimize the side effects associated with glucocorticoid receptor agonist therapy | HIGH POINT PHARMACEUTICALS, LLC | 2006-05-04 | — | — | US | claimed |
| EP-1615697-A2 | NEW PYRAZOLO[1,5-A] PYRIMIDINE DERIVATIVES AND PHARMACEUTICAL USE THEREOF | NOVO NORDISK A/S (DK) | 2006-01-18 | — | — | EP | claimed |
| WO-2004089416-A2 | COMBINATION OF AN 11BETA-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND AN ANTIHYPERTENSIVE AGENT | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089471-A2 | NEW PYRAZOLO[1,5-a] PYRIMIDINES DERIVATIVES AND PHARMACEUTICAL USE THEREOF | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | claimed |
| WO-2004089415-A2 | COMBINATIONS OF AN 11β-HYDROXYSTEROID DEHYDROGENASE TYPE 1 INHIBITOR AND A GLUCOCORTICOID RECEPTOR AGONIST | NOVO NORDISK A/S (DK) | 2004-10-21 | — | — | WO | claimed |
| EP-0951468-A4 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES INC (US) | 2001-06-06 | — | — | EP | claimed |
| US-6093829-A | Silicone monomers and oligomers having a carboxyl functional group thereon | MONA INDUSTRIES, INC. (US) | 2000-07-25 | — | — | US | claimed |
| EP-0951468-A1 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES, INC. (US) | 1999-10-27 | — | — | EP | claimed |
| US-5780639-A | COUPLING AGENTS, ADHESION PROMOTERS, CROSSLINKING AGENTS | MONA INDUSTRIES, INC. (US) | 1998-07-14 | — | — | US | claimed |
| WO-1998022478-A1 | SILICONE MONOMERS AND OLIGOMERS HAVING A CARBOXYL FUNCTIONAL GROUP THEREON | MONA INDUSTRIES, INC. (US) | 1998-05-28 | — | — | WO | claimed |
| EP-0520880-A1 | Cephalosporines having a 2-thia cephem ring, process for their preparation, pharmaceutical compositions containing them, their application as medicaments and intermediates | ROUSSEL UCLAF (FR) | 1992-12-30 | — | — | EP | claimed |
| EP-0028449-A1 | Chromanol derivatives, a process for their preparation and a pharmaceutical composition comprising them | BEECHAM GROUP PLC (GB) | 1981-05-13 | — | — | EP | claimed |