Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.35 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | CRACR2A | Q9BSW2 | 2/20 | 0.33 |
| ▸ | GPBAR1 | Q8TDU6 | 2/20 | 0.32 |
| ▸ | MAOA | P21397 | 1/20 | 0.31 |
| ▸ | MAOB | P27338 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | ATM | Q13315 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30251387 | 0.81 | MAPT (0.49) | MAPTGAAALDH1A1MAOAMAOB | |
| SCHEMBL2870042 | 0.69 | ABCC8 (0.39) | ABCC8KCNJ11CRACR2A | |
| Hydrochloric Acid SCHEMBL2870045 | 0.66 | ABCC8 (0.41) | ABCC8KCNJ11ALDH1A1 | |
| SCHEMBL12852364 | 0.65 | MEN1 (0.49) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL2866681 | 0.62 | MAPT (0.41) | MAPTGAAABCC8KCNJ11ALDH1A1 | |
| SCHEMBL3149268 | 0.61 | LMNA (0.46) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL27929683 | 0.60 | ALOX5 (0.44) | MAPTGAAALDH1A1MEN1KMT2A | |
| SCHEMBL2862045 | 0.60 | ABCC8 (0.50) | ABCC8KCNJ11ALDH1A1KMT2A | |
| SCHEMBL12852342 | 0.60 | ABCC8 (0.50) | MAPTABCC8KCNJ11ALDH1A1KMT2A | |
| SCHEMBL2872524 | 0.60 | ABCC8 (0.58) | ABCC8KCNJ11ALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010025870-A1 | SYNERGISTIC COMBINATIONS OF THIADIAZOL CARBONIC ACID DERIVATIVES | BAYER CROPSCIENCE AG (DE) | 2010-03-11 | — | — | WO | disclosed |