SCHEMBL3149268

SCHEMBL3149268

CC(=O)N(Cl)c1ccc(C)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.46
KDM4E B2RXH2 1/20 0.46
ALDH1A1 P00352 7/20 0.46
SMN1; SMN2 Q16637 3/20 0.46
RAB9A P51151 2/20 0.46
TSHR P16473 1/20 0.42
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
HTT P42858 3/20 0.40
TDP1 Q9NUW8 2/20 0.40
KEAP1 Q14145 1/20 0.37
NFE2L2 Q16236 1/20 0.37
PKM P14618 2/20 0.37
ATM Q13315 2/20 0.37
NPSR1 Q6W5P4 2/20 0.37
HPGD P15428 1/20 0.37
NLRP1 Q9C000 1/20 0.37
GAA P10253 1/20 0.37
MEN1 O00255 1/20 0.37
NTSR1 P30989 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12200280 0.91 ALDH1A1 (0.39) LMNAKDM4EALDH1A1SMN1; SMN2RAB9A
SCHEMBL3150016 0.82 LMNA (0.46) LMNAKDM4EALDH1A1SMN1; SMN2RAB9A
SCHEMBL10863831 0.82 CA2 (0.40) LMNAKDM4EALDH1A1RAB9ATSHR
SCHEMBL27929683 0.80 ALOX5 (0.44) LMNAKDM4EALDH1A1SMN1; SMN2RAB9A
SCHEMBL2724523 0.79 NPSR1 (0.46) LMNAALDH1A1SMN1; SMN2RAB9ATSHR
SCHEMBL10920659 0.78 HPGD (0.48) LMNAALDH1A1SMN1; SMN2RAB9ANPSR1
SCHEMBL8014181 0.78 ALDH1A1 (0.44) LMNAKDM4EALDH1A1SMN1; SMN2RAB9A
SCHEMBL1031452 0.77 ALDH1A1 (0.45) ALDH1A1SMN1; SMN2RAB9ATSHRTDP1
SCHEMBL11113066 0.77 RAB9A (0.43) LMNAKDM4EALDH1A1SMN1; SMN2RAB9A
SCHEMBL27388740 0.77 ALDH1A1 (0.39) LMNAALDH1A1SMN1; SMN2RAB9ATSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 23 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-1135506-A None JP disclosed
EP-1749880-B1 Cleaning compositions and methods RECKITT BENCKISER UK LTD (GB) 2013-04-17 EP disclosed
US-8258092-B2 Cleaning compositions and methods RECKITT BENCKISER (UK) LIMITED (GB) 2012-09-04 US disclosed
EP-2157161-A1 Improvements in or relating to cleaning Reckitt-Benckiser (UK) Limited (GB) 2010-02-24 EP disclosed
US-7638470-B2 Cleaning RECKITT BENCKISER (UK) LIMITED (GB) 2009-12-29 US disclosed
EP-1771537-B1 IMPROVEMENTS IN OR RELATING TO CLEANING RECKITT BENCKISER UK LTD (GB) 2009-12-16 EP disclosed
US-20080230095-A1 Cleaning Compositions and Methods RECKITT BENCKISER (UK) LIMITED (GB) 2008-09-25 US disclosed
US-20070254824-A1 Multicompartment container for a liquid cleaning compound in combination with a solid oxidation catalyst which when in contact with the cleaner causes a reaction to increase its oxidation power, or change its pH, cause gas evolution, or release heat; antisoilants; tough stains; fabrics; surfaces RECKITT BENCKISER (UK) LIMITED (GB) 2007-11-01 US disclosed
EP-1360270-B1 AUTOMATIC DISHWASHING COMPOSITIONS COMPRISING BLOOMING PERFUME AND BASE MASKING INGREDIENTS PROCTER & GAMBLE (US) 2007-05-16 EP disclosed
EP-1771537-A1 IMPROVEMENTS IN OR RELATING TO CLEANING Reckitt Benckiser Healthcare (UK) Limited (GB) 2007-04-11 EP disclosed
WO-2006010889-A1 IMPROVEMENTS IN OR RELATING TO CLEANING RECKITT BENCKISER (UK) LIMITED (GB) 2006-02-02 WO disclosed
EP-0888441-B1 PROCESS OF MANUFACTURING OF BUILT AUTOMATIC DISHWASHING COMPOSITIONS COMPRISING BLOOMING PERFUME PROCTER & GAMBLE (US) 2004-10-06 EP disclosed
US-20040138078-A1 Automatic dishwashing compositions comprising blooming perfume and base masking ingredients CLARE JONATHAN RICHARD (GB) 2004-07-15 US disclosed
EP-0888446-B1 TOILET BOWL DETERGENT SYSTEM CONTAINING BLOOMING PERFUME PROCTER & GAMBLE (US) 2003-10-15 EP disclosed
US-20020169091-A1 Automatic dishwashing compositions comprising blooming perfume and base masking ingredients PROCTER & GAMBLE COMPANY, THE 2002-11-14 US disclosed
US-6143707-A CLEANING AND STAIN REMOVAL AND PROVIDE A POSITIVE SCENT; FOR WASHING KITCHENWARE THE PROCTER & GAMBLE COMPANY (US) 2000-11-07 US disclosed
US-6001789-A BLOCK DETERGENT COMPRISING MOISTURE ACTIVATED ENCAPSULATED PERFUME PARTICLES, SURFACTANT, DETERGENT BUILDER AND SYSTEM FOR PROVIDING CONCENTRATION OF CLEANING COMPOUND TO TOILET WATER THE PROCTER & GAMBLE COMPANY (US) 1999-12-14 US disclosed
WO-1997007188-A1 HAND DISHWASHING POWDER WITH CHLORINE BLEACH THE PROCTER & GAMBLE COMPANY (US) 1997-02-27 WO disclosed
JP-H01135506-A METHOD FOR PRODUCING PURIFIED WATER TORAY IND INC 1989-05-29 JP disclosed
US-4049609-A HYPOCHLORITE SINTETICA AMERICANA, INC. (US) 1977-09-20 US disclosed