Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DGAT1 | O75907 | 1/20 | 0.42 |
| ▸ | MTOR | P42345 | 4/20 | 0.34 |
| ▸ | PIK3CA | P42336 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.32 |
| ▸ | PDE5A | O76074 | 2/20 | 0.31 |
| ▸ | BRD4 | O60885 | 1/20 | 0.31 |
| ▸ | CREBBP | Q92793 | 1/20 | 0.31 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.31 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
| ▸ | IGF1R | P08069 | 1/20 | 0.31 |
| ▸ | SRC | P12931 | 1/20 | 0.31 |
| ▸ | FLT4 | P35916 | 1/20 | 0.31 |
| ▸ | KDR | P35968 | 1/20 | 0.31 |
| ▸ | FLT3 | P36888 | 1/20 | 0.31 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.31 |
| ▸ | TEK | Q02763 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32659847 | 0.86 | DGAT1 (0.35) | DGAT1MTORPIK3CAMAPTPIK3CD | |
| SCHEMBL31047151 | 0.79 | NPC1 (0.32) | MAPTNPC1BRD4CREBBP | |
| SCHEMBL31047155 | 0.76 | NPC1 (0.33) | MAPTNPC1 | |
| SCHEMBL32659833 | 0.74 | NPC1 (0.45) | MTORMAPTPIK3CDNPC1BRD4 | |
| SCHEMBL32659858 | 0.74 | NPC1 (0.35) | MAPTNPC1 | |
| SCHEMBL32659809 | 0.71 | NPC1 (0.36) | DGAT1MAPTNPC1ATMMETAP2 | |
| SCHEMBL32659868 | 0.71 | NPC1 (0.38) | MAPTNPC1PDE3BPDE3A | |
| SCHEMBL32659866 | 0.70 | MAPT (0.36) | DGAT1MAPTNPC1ATM | |
| SCHEMBL32659885 | 0.69 | NPC1 (0.32) | NPC1 | |
| SCHEMBL32659805 | 0.67 | NPC1 (0.38) | DGAT1MAPTNPC1PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678641-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |