⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32659868 | 0.84 | NPC1 (0.38) | — | |
| SCHEMBL32659809 | 0.69 | NPC1 (0.36) | — | |
| SCHEMBL32659846 | 0.67 | NPC1 (0.35) | — | |
| SCHEMBL32659889 | 0.66 | DGAT1 (0.33) | — | |
| SCHEMBL32659866 | 0.66 | MAPT (0.36) | — | |
| SCHEMBL32659865 | 0.66 | NPC1 (0.33) | — | |
| SCHEMBL32659805 | 0.64 | NPC1 (0.38) | — | |
| SCHEMBL32659841 | 0.64 | ATM (0.37) | — | |
| SCHEMBL32659833 | 0.61 | NPC1 (0.45) | — | |
| SCHEMBL32659858 | 0.59 | NPC1 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4678641-A1 | QUINOLINONE COMPOUND AND NAPHTHYRIDINONE COMPOUND AND USE THEREOF | Shanghai Helioson Pharmaceutical Co., Ltd. (CN) | 2026-01-14 | — | — | EP | disclosed |