Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CASP3 | P42574 | 2/20 | 0.72 |
| ▸ | RAB9A | P51151 | 13/20 | 0.69 |
| ▸ | NPC1 | O15118 | 12/20 | 0.69 |
| ▸ | SMN1; SMN2 | Q16637 | 8/20 | 0.69 |
| ▸ | TSHR | P16473 | 3/20 | 0.69 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | TP53 | P04637 | 4/20 | 0.59 |
| ▸ | MEN1 | O00255 | 3/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.59 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.59 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.59 |
| ▸ | RELA | Q04206 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 7/20 | 0.55 |
| ▸ | HSD17B10 | Q99714 | 6/20 | 0.54 |
| ▸ | POLB | P06746 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.47 |
| ▸ | HPGD | P15428 | 4/20 | 0.47 |
| ▸ | USP2 | O75604 | 3/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13930818 | 0.85 | CASP3 (0.74) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL13930846 | 0.85 | NPC1 (0.76) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL3265418 | 0.84 | CASP3 (0.72) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL3266359 | 0.84 | CASP3 (0.72) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL3261588 | 0.84 | CASP3 (1.00) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL2458259 | 0.82 | NPC1 (1.00) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL12171145 | 0.80 | CASP3 (0.67) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL11715629 | 0.76 | CASP3 (0.60) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL2462807 | 0.75 | NPC1 (1.00) | CASP3RAB9ANPC1SMN1; SMN2TSHR | |
| SCHEMBL414494 | 0.74 | TAAR1 (0.61) | RAB9ANPC1TSHRALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. | 2013-11-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| EP-2184989-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Divergence, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (7 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | CASP3 477/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20130296166-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | ATL3, NOP2, PTMS | CASP3 654/4885RAB9A 3486/4885NPC1 3394/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | CASP3 634/4885RAB9A 4578/4885NPC1 4073/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | CASP3 477/4885RAB9A 3412/4885NPC1 2871/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | CASP3 477/4885RAB9A 3412/4885NPC1 2871/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.