SCHEMBL32662677

SCHEMBL32662677

NS(=O)(=O)OC[C@H]1O[C@@H](n2cnc3c(NCC4COCCOCCOCCOCCO4)ncnc32)[C@H](O)[C@@H]1O

nearest known ligand 0.57

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
▸ UBA6 A0AVT1 1/20 0.57
▸ ATG7 O95352 1/20 0.57
▸ UBA7 P41226 1/20 0.57
▸ NAE1 Q13564 1/20 0.57
▸ UBA3 Q8TBC4 1/20 0.57
▸ SAE1 Q9UBE0 1/20 0.57
▸ ADORA1 P30542 14/20 0.55
▸ ADORA3 P0DMS8 2/20 0.52
▸ SLC28A1 O00337 1/20 0.50
▸ ADORA2A P29274 1/20 0.50
▸ ADORA2B P29275 1/20 0.50
▸ SLC29A1 Q99808 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL32662675 0.89 ADORA1 (0.60) UBA6ATG7UBA7NAE1UBA3
SCHEMBL32661823 0.83 ADORA1 (0.65) UBA6ATG7UBA7NAE1UBA3
SCHEMBL1798569 0.83 ADORA1 (0.65) UBA6ATG7UBA7NAE1UBA3
SCHEMBL1798642 0.82 UBA6 (0.58) UBA6ATG7UBA7NAE1UBA3
SCHEMBL32662224 0.82 ADORA1 (0.74) UBA6ATG7UBA7NAE1UBA3
SCHEMBL1796399 0.81 UBA6 (0.61) UBA6ATG7UBA7NAE1UBA3
SCHEMBL32662540 0.81 SLC29A1 (0.64) UBA6ATG7UBA7NAE1UBA3
SCHEMBL32662283 0.80 ADORA1 (0.66) UBA6ATG7UBA7NAE1UBA3
SCHEMBL32662240 0.80 UBA6 (0.61) UBA6ATG7UBA7NAE1UBA3
SCHEMBL32661927 0.80 LMNA (0.73) UBA6ATG7UBA7NAE1UBA3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260015592-A1 NEDDYLATION-ACTIVATING ENZYME INHIBITORS AS VIRAL SENSITIZERS AND USES THEREOF OTTAWA HOSPITAL RESEARCH INSTITUTE (CA) 2026-01-15 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260015592-A1 NEDDYLATION-ACTIVATING ENZYME INHIBITORS AS VIRAL SENSITIZERS AND USES THEREOF NAE1, NEDD8, UBA3 UBA6 153/4885ATG7 884/4885UBA7 269/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.

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