Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLAU | P00749 | 11/20 | 0.64 |
| ▸ | PLG | P00747 | 5/20 | 0.64 |
| ▸ | F2 | P00734 | 5/20 | 0.64 |
| ▸ | KLK1 | P06870 | 4/20 | 0.64 |
| ▸ | PRSS1 | P07477 | 4/20 | 0.64 |
| ▸ | KLKB1 | P03952 | 3/20 | 0.64 |
| ▸ | F12 | P00748 | 2/20 | 0.62 |
| ▸ | C1S | P09871 | 1/20 | 0.59 |
| ▸ | PLAT | P00750 | 3/20 | 0.50 |
| ▸ | ASIC3 | Q9UHC3 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | MEN1 | O00255 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | MAPT | P10636 | 1/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.48 |
| ▸ | F10 | P00742 | 1/20 | 0.47 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL613558 | 0.79 | LCK (0.62) | PLAUPLGF2PRSS1KLKB1 | |
| SCHEMBL15644255 | 0.79 | ALDH1A1 (0.48) | PLAUPLGF2KLK1PRSS1 | |
| SCHEMBL3370031 | 0.78 | PLAU (1.00) | PLAUPLGF2KLK1PRSS1 | |
| SCHEMBL29941688 | 0.78 | PLAU (1.00) | PLAUPLGF2KLK1PRSS1 | |
| SCHEMBL2100964 | 0.78 | CYP2A6 (0.45) | PLAUPLGF2KLK1PRSS1 | |
| SCHEMBL5431020 | 0.77 | PLAU (0.55) | PLAUPLGF2KLK1PRSS1 | |
| SCHEMBL204318 | 0.77 | LMNA (0.59) | PLAUF2PRSS1F12C1S | |
| SCHEMBL3301671 | 0.77 | F12 (1.00) | PLAUPLGF2KLK1PRSS1 | |
| SCHEMBL7362642 | 0.77 | PLAU (0.72) | PLAUPLGF2KLK1PRSS1 | |
| SCHEMBL31499215 | 0.77 | F12 (1.00) | PLAUPLGF2KLK1PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-121362142-A | Preparation method of nafamostat mesylate | 鲁南制药集团股份有限公司 | 2026-01-20 | — | — | CN | disclosed |