Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM5 | P41594 | 4/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.35 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.34 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.33 |
| ▸ | SLC22A12 | Q96S37 | 1/20 | 0.33 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL21718820 | 0.81 | HTT (0.38) | GRM5HTTGAAALDH1A1L3MBTL1 | |
| SCHEMBL24858154 | 0.75 | TRPV4 (0.37) | HTTGAAALDH1A1CYP11B2L3MBTL1 | |
| SCHEMBL16648624 | 0.74 | PIK3CD (0.45) | HTTGAAALDH1A1L3MBTL1KDM4E | |
| SCHEMBL17964135 | 0.74 | HTT (0.43) | HTTGAAALDH1A1CYP3A4CYP2C19 | |
| SCHEMBL231937 | 0.74 | TDP1 (0.44) | GRM5HTTGAAALDH1A1CYP11B2 | |
| SCHEMBL31221920 | 0.74 | TDP1 (0.44) | GRM5HTTGAAALDH1A1CYP11B2 | |
| SCHEMBL30999851 | 0.73 | ASPH (0.41) | HTTKDM4EMRGPRX4SLC22A12 | |
| SCHEMBL29721809 | 0.72 | ALDH1A1 (0.55) | HTTGAAALDH1A1L3MBTL1MAPT | |
| SCHEMBL7940220 | 0.71 | CHRNB2 (0.42) | GRM5HTTGAAALDH1A1CYP11B2 | |
| SCHEMBL15674757 | 0.71 | PLAU (0.42) | HTTALDH1A1CYP11B2MAPTKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4680608-A1 | 2,6-DIHYDRO-7H-PYRAZOLO[3,4-C]PYRIDIN-7-ONE DERIVATIVES AS ANTI-MALARIAL AGENTS | MMV Medicines for Malaria Venture (CH) | 2026-01-21 | — | — | EP | disclosed |