Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 4/20 | 0.62 |
| ▸ | RAB9A | P51151 | 3/20 | 0.62 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 7/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.56 |
| ▸ | HPGD | P15428 | 6/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.56 |
| ▸ | MEN1 | O00255 | 5/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.56 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | HPGDS | O60760 | 1/20 | 0.51 |
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.49 |
| ▸ | NPC1 | O15118 | 2/20 | 0.49 |
| ▸ | GAA | P10253 | 2/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.49 |
| ▸ | CASP3 | P42574 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8888012 | 0.87 | MAPT (0.64) | POLBRAB9APDE10AMAPTALDH1A1 | |
| SCHEMBL9048218 | 0.86 | MAPT (0.58) | POLBRAB9APDE10AMAPTALDH1A1 | |
| SCHEMBL17279985 | 0.80 | HPGD (0.60) | POLBRAB9APDE10AMAPTALDH1A1 | |
| SCHEMBL17280251 | 0.80 | RAB9A (0.87) | POLBRAB9AMAPTALDH1A1HPGD | |
| SCHEMBL1230353 | 0.78 | RAB9A (1.00) | POLBRAB9AMAPTALDH1A1HPGD | |
| SCHEMBL17279801 | 0.76 | RAB9A (0.96) | POLBRAB9AMAPTALDH1A1HPGD | |
| SCHEMBL20340353 | 0.74 | RAB9A (0.84) | POLBRAB9AMAPTALDH1A1HPGD | |
| SCHEMBL17345709 | 0.74 | RAB9A (0.92) | POLBRAB9AMAPTALDH1A1HPGD | |
| SCHEMBL19049229 | 0.74 | RAB9A (0.92) | POLBRAB9AMAPTALDH1A1HPGD | |
| SCHEMBL17279797 | 0.74 | RAB9A (0.92) | POLBRAB9AMAPTALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 64 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-10827753-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2020-11-10 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-11-14 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-10-31 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-10375958-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2019-08-13 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | MONSANTO TECHNOLOGY LLC (US) | 2019-01-24 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| US-8435999-B2 | Compositions and methods for controlling nematodes | MONSANTO TECHNOLOGY LLC (US) | 2013-05-07 | — | — | US | disclosed |
| CN-101820761-A | Compositions and methods for controlling nematodes | DIVERGENCE INC | 2010-09-01 | — | — | CN | disclosed |
| EP-2184989-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | Divergence, Inc. (US) | 2010-05-19 | — | — | EP | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| WO-2009023721-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | DIVERGENCE, INC. (US) | 2009-02-19 | — | — | WO | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | MONSANTO TECHNOLOGY LLC | 2009-02-19 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10827753-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | POLB 2379/4885RAB9A 3412/4885PDE10A 1964/4885 |
| US-20190021325-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | POLB 2379/4885RAB9A 3412/4885PDE10A 1964/4885 |
| US-20190343120-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | POLB 2379/4885RAB9A 3412/4885PDE10A 1964/4885 |
| US-20090048311-A1 | Compostions and Methods for Controlling Nematodes | NOP2, MT-CO3, CLPX | POLB 1134/4885RAB9A 4578/4885PDE10A 2781/4885 |
| US-10375958-B2 | Compositions and methods for controlling nematodes | NOP2, ATL3, CYCS | POLB 2379/4885RAB9A 3412/4885PDE10A 1964/4885 |
| US-20190327967-A1 | COMPOSITIONS AND METHODS FOR CONTROLLING NEMATODES | NOP2, ATL3, CYCS | POLB 2379/4885RAB9A 3412/4885PDE10A 1964/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.