Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HTR7 | P34969 | 3/20 | 0.36 |
| ▸ | L3MBTL3 | Q96JM7 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | MGLL | Q99685 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | MBTD1 | Q05BQ5 | 1/20 | 0.34 |
| ▸ | TP53BP1 | Q12888 | 1/20 | 0.34 |
| ▸ | GFER | P55789 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | NPY5R | Q15761 | 1/20 | 0.34 |
| ▸ | GUSB | P08236 | 1/20 | 0.33 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665450 | 0.93 | NOTUM (0.40) | ALDH1A1NOTUML3MBTL3L3MBTL1MGLL | |
| SCHEMBL32665174 | 0.93 | NOTUM (0.40) | ALDH1A1NOTUML3MBTL3L3MBTL1MGLL | |
| SCHEMBL32665143 | 0.86 | L3MBTL3 (0.37) | ALDH1A1L3MBTL3L3MBTL1SMN1; SMN2MBTD1 | |
| SCHEMBL32665454 | 0.85 | FFAR4 (0.38) | ALDH1A1HTR7SMN1; SMN2TSHR | |
| SCHEMBL32665021 | 0.82 | HTR1A (0.38) | NOTUMHTR7SMN1; SMN2 | |
| SCHEMBL32665470 | 0.82 | HTR6 (0.40) | HTR7L3MBTL3L3MBTL1MBTD1TP53BP1 | |
| SCHEMBL32665195 | 0.82 | HRH1 (0.37) | ALDH1A1NOTUMSMN1; SMN2MAPT | |
| SCHEMBL32665569 | 0.81 | OPRM1 (0.44) | ALDH1A1MAPT | |
| SCHEMBL32665624 | 0.80 | VCP (0.42) | ALDH1A1NOTUMSMN1; SMN2MAPTTSHR | |
| SCHEMBL32665356 | 0.79 | DRD2 (0.34) | ALDH1A1NOTUML3MBTL3L3MBTL1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | ALDH1A1 3714/4885NOTUM 4135/4885HTR7 4312/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.