Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | HPGD | P15428 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | TNIK | Q9UKE5 | 1/20 | 0.48 |
| ▸ | MME | P08473 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | FAAH | O00519 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | MMP1 | P03956 | 1/20 | 0.46 |
| ▸ | MMP9 | P14780 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665167 | 0.85 | ALDH1A1 (0.45) | ALDH1A1LMNAPOLBHPGDHTT | |
| SCHEMBL32665144 | 0.79 | LTA4H (0.42) | ALDH1A1MEN1KMT2ACYP2D6CYP2C19 | |
| SCHEMBL4591580 | 0.79 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBHPGDHTT | |
| SCHEMBL1427542 | 0.78 | ALDH1A1 (0.58) | ALDH1A1LMNAPOLBHPGDHTT | |
| SCHEMBL32665364 | 0.78 | S1PR5 (0.35) | ALDH1A1KDM4EMEN1KMT2AFAAH | |
| SCHEMBL24770881 | 0.76 | MMP1 (0.54) | ALDH1A1LMNAPOLBHPGDHTT | |
| SCHEMBL27042826 | 0.76 | MMP1 (0.48) | ALDH1A1LMNAPOLBHPGDHTT | |
| SCHEMBL4592940 | 0.76 | TNIK (0.50) | ALDH1A1LMNAPOLBHPGDHTT | |
| SCHEMBL28761346 | 0.75 | CYP2D6 (0.56) | ALDH1A1POLBMAPK1CYP3A4CYP2D6 | |
| SCHEMBL26656812 | 0.75 | ALDH1A1 (0.54) | ALDH1A1LMNAPOLBHPGDHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260022094-A1 | Compounds for the Treatment of Neurodegenerative Diseases | CELGENE CORPORATION (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260022094-A1 | Compounds for the Treatment of Neurodegenerative Diseases | S1PR5, CLN6, S1PR1 | ALDH1A1 1518/4885LMNA 564/4885POLB 4502/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.