Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.39 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.38 |
| ▸ | TSHR | P16473 | 2/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HIF1A | Q16665 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
| ▸ | BACE1 | P56817 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | DRD4 | P21917 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | USP2 | O75604 | 2/20 | 0.36 |
| ▸ | P4HB | P07237 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL32665228 | 0.85 | CHRM2 (0.46) | CYP2D6CHRM2CHRM3LMNAKMT2A | |
| SCHEMBL32665137 | 0.80 | HRH3 (0.36) | CYP2D6LMNAKMT2AMEN1CYP2C9 | |
| SCHEMBL32665615 | 0.80 | TDP1 (0.41) | LMNAKMT2AMEN1CYP2C9CYP1A2 | |
| SCHEMBL32665369 | 0.77 | ACHE (0.43) | CYP2D6CHRM2CHRM3LMNAKMT2A | |
| SCHEMBL32665089 | 0.73 | DOCK5 (0.35) | LMNASIGMAR1ALDH1A1MAPK1 | |
| SCHEMBL32665432 | 0.73 | NPSR1 (0.36) | CHRM2CHRM3KMT2AMEN1SIGMAR1 | |
| SCHEMBL32665508 | 0.72 | CCR8 (0.39) | CYP2D6CHRM2CHRM3SIGMAR1CYP3A4 | |
| SCHEMBL32665203 | 0.70 | HTR7 (0.42) | CYP2D6KMT2AMEN1CYP1A2DRD4 | |
| SCHEMBL12642507 | 0.70 | CYP2D6 (0.76) | CYP2D6CHRM2CHRM3KMT2AMEN1 | |
| SCHEMBL5428090 | 0.69 | DRD4 (0.63) | LMNASIGMAR1ACHEBACE1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | TOPAZ THERAPEUTICS INC (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021192-A1 | PROTEINS HAVING A COVALENT WARHEAD | RIOX2, ORC3, DCLRE1A | CYP2D6 4329/4885CHRM2 4716/4885CHRM3 4644/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.