Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KIF11 | P52732 | 11/20 | 0.32 |
| ▸ | SIRT2 | Q8IXJ6 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30976149 | 0.83 | PLA2G2A (0.35) | KIF11KCNH2 | |
| SCHEMBL30976095 | 0.82 | PLA2G2A (0.37) | KIF11KCNH2 | |
| SCHEMBL30976195 | 0.82 | PLA2G2A (0.37) | KIF11KCNH2 | |
| SCHEMBL30976245 | 0.82 | PLA2G2A (0.37) | KIF11KCNH2 | |
| SCHEMBL30976214 | 0.82 | PLA2G2A (0.37) | KIF11KCNH2 | |
| SCHEMBL30976172 | 0.82 | PLA2G2A (0.37) | KIF11KCNH2 | |
| SCHEMBL30976129 | 0.82 | PLA2G2A (0.37) | KIF11KCNH2 | |
| SCHEMBL23201022 | 0.81 | KCNH2 (0.37) | SIRT2KCNH2 | |
| SCHEMBL25397880 | 0.79 | HDAC1 (0.35) | — | |
| SCHEMBL25401369 | 0.79 | KCNH2 (0.31) | KIF11KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20260021055-A1 | Asymmetric Piperazine-Based Cationic Lipids | TRANSLATE BIO, INC. (US) | 2026-01-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20260021055-A1 | Asymmetric Piperazine-Based Cationic Lipids | SGMS2, SPTLC2, SGMS1 | KIF11 2343/4885SIRT2 1796/4885KCNH2 2132/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.