SCHEMBL7936142

SCHEMBL7936142

Cc1ccc(Nc2cc(C)ccc2O)cc1

nearest known ligand 0.58

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CXCR2 P25025 1/20 0.58
GAA P10253 6/20 0.52
MEN1 O00255 3/20 0.52
KMT2A Q03164 3/20 0.52
L3MBTL1 Q9Y468 2/20 0.52
G6PD P11413 1/20 0.52
TRPA1 O75762 1/20 0.48
TDP1 Q9NUW8 2/20 0.46
TP53 P04637 1/20 0.46
KCNMA1 Q12791 2/20 0.46
EGFR P00533 1/20 0.46
MAPT P10636 3/20 0.46
RAPGEF4 Q8WZA2 1/20 0.45
HPGD P15428 1/20 0.45
SMN1; SMN2 Q16637 2/20 0.45
HSP90AA1 P07900 1/20 0.44
NPC1 O15118 2/20 0.44
RAB9A P51151 1/20 0.44
KDM4E B2RXH2 1/20 0.44
GFER P55789 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7934312 0.88 CXCR2 (0.73) CXCR2GAAMEN1KMT2AL3MBTL1
SCHEMBL17526960 0.82 CXCR2 (0.58) CXCR2GAAMEN1KMT2AL3MBTL1
SCHEMBL30686692 0.79 MAPT (0.60) CXCR2GAAMEN1KMT2AL3MBTL1
SCHEMBL5823760 0.79 MAPT (0.60) CXCR2GAAMEN1KMT2AL3MBTL1
SCHEMBL24459914 0.79 GAA (0.47) CXCR2GAAMEN1KMT2AL3MBTL1
SCHEMBL17858219 0.78 RAPGEF4 (0.61) GAAMEN1KMT2AL3MBTL1G6PD
SCHEMBL17063545 0.78 HPGD (0.59) CXCR2GAAMEN1KMT2AL3MBTL1
SCHEMBL7830951 0.77 NPSR1 (0.58) CXCR2GAAMEN1KMT2AL3MBTL1
SCHEMBL29494159 0.76 TRPA1 (0.54) CXCR2GAAMEN1KMT2ATRPA1
SCHEMBL1921826 0.76 RAPGEF4 (0.63) GAAMEN1KMT2AL3MBTL1G6PD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1140772-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2001-10-10 EP claimed
WO-2000037412-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2000-06-29 WO claimed
EP-1140772-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2001-10-10 EP disclosed
WO-2000037412-A1 COMPOSITION AND METHOD FOR INHIBITING RADICAL POLYMERISATION OF ETHYLENICALLY UNSATURATED ALIPHATIC MONOMERS RHODIA CHIMIE (FR) 2000-06-29 WO disclosed